Charlotte Vanpoucke

TL;DR: The observed telomere loss in newborns by prenatal air pollution exposure indicates less buffer for postnatal influences of factors decreasing telomeres length during life, and improvements in air quality may promote molecular longevity from birth onward.

TL;DR: The results suggest that mtDNA content can be one of the potential mediators of the association between prenatal air pollution exposure and birth weight.

TL;DR: This work presents a novel approach to calculate the daily exposure to air pollution using mobile phone data of approximately 5 million mobile phone users living in Belgium, and incorporates individual travel patterns using their location inferred from their use of the mobile phone network.

TL;DR: PM-associated increased mitochondrial oxidative DNA damage during pregnancy in both mothers and their newborns was found, showing that particulate air pollution exposure in early life plays a role in increasing systemic oxidative stress, at the level of the mitochondria, both in mother and foetus.

TL;DR: The findings suggest that the estimated effects of PM2.5 exposure on the telomere–mitochondrial axis of aging may play an important role in chronic health effects in the elderly.