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Cheyenne Hurst
Researcher at Emory University
Publications - 10
Citations - 158
Cheyenne Hurst is an academic researcher from Emory University. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 2, co-authored 4 publications receiving 43 citations.
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Journal ArticleDOI
Integrated Proteomics Reveals Brain-Based Cerebrospinal Fluid Biomarkers in Asymptomatic and Symptomatic Alzheimer’s Disease
Lenora Higginbotham,Lingyan Ping,Eric B. Dammer,Duc M. Duong,Maotian Zhou,Marla Gearing,Cheyenne Hurst,Jonathan D. Glass,Stewart A. Factor,Erik C. B. Johnson,Ihab Hajjar,James J. Lah,Allan I. Levey,Nicholas T. Seyfried +13 more
TL;DR: Results are a promising step toward a network-based biomarker tool for AD clinical applications and identify cerebrospinal fluid biomarkers representing a wide spectrum of AD pathophysiology.
Journal ArticleDOI
Clustered Kv2.1 decreases dopamine transporter activity and internalization.
Joseph J. Lebowitz,Jose A. Pino,Phillip Mackie,Min Lin,Cheyenne Hurst,Keeley Divita,Anthony Collins,Dimitri N. Koutzoumis,Gonzalo E. Torres,Habibeh Khoshbouei +9 more
TL;DR: The results suggest that Kv2.1 clusters exert a spatially discrete homeostatic braking mechanism on DAT by inducing a relative increase in inward-facing transporters.
Journal ArticleDOI
Phosphorylation regulates arginine-rich RNA-binding protein solubility and oligomerization
Sean R. Kundinger,Eric B. Dammer,Luming Yin,Cheyenne Hurst,Sarah Shapley,Lingyan Ping,Sohail Khoshnevis,Homa Ghalei,Duc M. Duong,Nicholas T. Seyfried +9 more
TL;DR: In this article, the authors showed that posttranslational modifications such as phosphorylation of RNA-binding proteins (RBPs) regulate several critical steps in RNA metabolism, including spliceosome assembly, alternative splicing, and mRNA export.
Journal ArticleDOI
Integrated Proteomics to Understand the Role of Neuritin (NRN1) as a Mediator of Cognitive Resilience to Alzheimer’s Disease
Cheyenne Hurst,Derian A. Pugh,Measho Abreha,Duc M. Duong,Eric B. Dammer,David A. Bennett,Jeremy H. Herskowitz,Nicholas T. Seyfried +7 more
TL;DR: In this paper , a comprehensive network-based approach from cases clinically and pathologically defined as asymptomatic AD to map resilience-associated pathways and extend mechanistic validation was presented.
Journal ArticleDOI
Cross-Platform Synaptic Network Analysis of Human Entorhinal Cortex Identifies TWF2 as a Modulator of Dendritic Spine Length
Courtney K. Walker,Kelsey M. Greathouse,Jennifer J. Tuscher,Eric B. Dammer,A. J. Weber,Evan Liu,Kendall A. Curtis,Benjamin D. Boros,Cameron D. Freeman,Jung Vin Seo,Raksha Ramdas,Cheyenne Hurst,Duc M. Duong,Marla Gearing,Charles Murchison,Jeremy J. Day,Nicholas T. Seyfried,Jeremy H. Herskowitz +17 more
TL;DR: In this paper , a cross-platform pipeline was engineered to focus on synaptic processes in the entorhinal cortex (EC) of human patients, including controls, preclinical AD, and AD cases.