•Journal•ISSN: 1535-9476
Molecular & Cellular Proteomics
American Society for Biochemistry and Molecular Biology
About: Molecular & Cellular Proteomics is an academic journal published by American Society for Biochemistry and Molecular Biology. The journal publishes majorly in the area(s): Proteomics & Proteome. It has an ISSN identifier of 1535-9476. It is also open access. Over the lifetime, 4286 publications have been published receiving 339535 citations. The journal is also known as: Molecular and cellular proteomics & Mol Cell Proteomics.
Topics: Proteomics, Proteome, Biology, Phosphorylation, Medicine
Papers published on a yearly basis
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TL;DR: SILAC is a simple, inexpensive, and accurate procedure that can be used as a quantitative proteomic approach in any cell culture system and is applied to the relative quantitation of changes in protein expression during the process of muscle cell differentiation.
5,653 citations
TL;DR: It is found that inactivation of Upf1p and Xrn1p causes common as well as unique effects on protein expression, and the use of 4-fold multiplexing to enable relative protein measurements simultaneously with determination of absolute levels of a target protein using synthetic isobaric peptide standards.
4,411 citations
TL;DR: This work speculates on the reasons behind this large discrepancy between the expectations arising from proteomics and the realities of clinical diagnostics and suggests approaches by which protein-disease associations may be more effectively translated into diagnostic tools in the future.
4,062 citations
TL;DR: A new intensity determination and normalization procedure called MaxLFQ is developed that is fully compatible with any peptide or protein separation prior to LC-MS analysis, which accurately detects the mixing ratio over the entire protein expression range, with greater precision for abundant proteins.
3,732 citations
TL;DR: A quantitative transcriptomics analysis (RNA-Seq) is used to classify the tissue-specific expression of genes across a representative set of all major human organs and tissues and combined this analysis with antibody-based profiling of the same tissues.
2,512 citations