C
Chin-Siean Tay
Researcher at New York University
Publications - 3
Citations - 391
Chin-Siean Tay is an academic researcher from New York University. The author has contributed to research in topics: T cell & Antigen presentation. The author has an hindex of 3, co-authored 3 publications receiving 347 citations.
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Dendritic cell entrapment within the pregnant uterus inhibits immune surveillance of the maternal/fetal interface in mice
TL;DR: It is found that tissue reaction prevents DCs stationed at the maternal/fetal interface from migrating to the lymphatic vessels of the uterus and thus reaching the draining lymph nodes, and DC entrapment within the decidua minimizes immunogenic T cell exposure to fetal/placental antigens.
Journal ArticleDOI
Coordinate regulation of tissue macrophage and dendritic cell population dynamics by CSF-1
TL;DR: CSF-1 drives the homeostatic expansion of macrophages within the growing myometrium of pregnant mice by stimulating in situ proliferation and inducing monocyte precursor recruitment from the blood.
Journal ArticleDOI
Cis-Acting Pathways Selectively Enforce the Non-Immunogenicity of Shed Placental Antigen for Maternal CD8 T Cells
TL;DR: A transgenic system in which placental membranes are tagged with a strong surrogate antigen (ovalbumin) is addressed, outlining a major pathway governing the maternal immune response to the placenta and suggesting how tolerance to placental antigens can be maintained systemically without being detrimental to host defense.