Chiou Ling Cheng

TL;DR: In this article, the authors developed a five-gene signature that is closely associated with survival of patients with non-small-cell lung cancer (NSCLC) and evaluated the association between the level of expression and survival.

TL;DR: A five-gene signature that is closely associated with survival of patients with non-small-cell lung cancer is developed and validated with data from an independent cohort of 60 patients with NSCLC and with a set of published microarray data from 86 patients withNSCLC.

TL;DR: Using real-time RT-PCR, the authors obtained microRNA expressions in 112 NSCLC patients, which were divided into the training and testing sets, and used Cox regression and risk-score analysis to identify a five microRNA signatures for the prediction of treatment outcome.

TL;DR: The results suggest that upregulation of miR-141 upon enterovirus infection can facilitate viral propagation by expediting the translational switch, and identify a transcription factor, EGR1, which is partly responsible for mi R-141 induction in response to enterov virus infection.

TL;DR: HLJ1 is a novel tumor suppressor inNSCLC, and high HLJ1 expression is associated with reduced cancer recurrence and prolonged survival of NSCLC patients.