Chittalakkottu Sadasivan

TL;DR: It may be concluded from the structural and kinetics studies that the fatty acid, n‐hexadecanoic acid, is an inhibitor of phospholipase A2, hence, an anti‐inflammatory compound, validate the rigorous use of medicated oils rich in n‐ hexadecanoIC acid for the treatment of rheumatic symptoms in the traditional medical system of India, Ayurveda.

TL;DR: It is found that the mode of interactions and binding energy of BPA were similar to that of DEXA and cortisol, two known agonists of GR, which reveals that BPA can bind to GR as an agonist and may produce biological effectssimilar to that produced by glucocorticoids.

TL;DR: Results showed that the drugs Binifibrate and Bamifylline bind strongly to the enzyme active site and hence they can be repurposed against SARS-CoV-2, however, U.S Food and Drug Administration have withdrawn BinIFibrate from the market as it was having some adverse health effects on patients.

TL;DR: This review attempts to summarize changes in calcium signaling in the brain as a result of aging.

TL;DR: It can be suggested that the compound 4c might be a potential drug lead compound with AChE inhibitory activity, however, further pharmacokinetic studies are necessary to comment on the efficacy of the compound as a drug for AD.