C
Chris W. Lee
Publications - 2
Citations - 18
Chris W. Lee is an academic researcher. The author has contributed to research in topics: FGF19 & Liver disease. The author has an hindex of 1, co-authored 2 publications receiving 5 citations.
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Journal ArticleDOI
Developmental regulation of the gut-liver (FGF19-CYP7A1) axis in neonates.
Naureen Memon,Ian J. Griffin,Chris W. Lee,Aimee Herdt,Barry Weinberger,Thomas Hegyi,Mary Carayannopoulos,Lauren M. Aleksunes,Grace L. Guo +8 more
TL;DR: It is demonstrated that FGF19 is expressed at birth in preterm infants and decreases over time, even as enteral feeds increase, while CYP7A1 activity is developmentally regulated; its activity is undetectable prior to 30 weeks’ gestation and increases with advancing gestational age and volume ofEnteral feeds.
Journal ArticleDOI
Suppression of Bile Acid Synthesis in a Preterm Infant Receiving Prolonged Parenteral Nutrition
Naureen Memon,Chris W. Lee,Aimee Herdt,Barry Weinberger,Thomas Hegyi,Mary Carayannopoulos,Lauren M. Aleksunes,Grace L. Guo,Ian J. Griffin +8 more
TL;DR: CYP7A1 activity was gradually upregulated in healthy preterm infants but remained suppressed in the infant requiring prolonged PN, which was a case of a preterm infant who developed necrotizing enterocolitis and received exclusive PN for over 2 months.