C
Christa Sibilla Schreurs
Researcher at AkzoNobel
Publications - 7
Citations - 308
Christa Sibilla Schreurs is an academic researcher from AkzoNobel. The author has contributed to research in topics: Virus & Pseudorabies. The author has an hindex of 6, co-authored 7 publications receiving 273 citations.
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Journal ArticleDOI
Protection of Chickens From Newcastle and Marek's Diseases With a Recombinant Herpesvirus of Turkeys Vaccine Expressing the Newcastle Disease Virus Fusion Protein
Robin W. Morgan,Jack Gelb,Christa Sibilla Schreurs,Dieter Lutticken,John K. Rosenberger,Paul J. A. Sondermeijer +5 more
TL;DR: Recombinant HVT vaccines and the parent HVT strain provided similar levels of protection to chickens challenged with the very virulent RB1B strain of Marek's disease virus, indicating that insertion of foreign sequences into the HVT genome did not compromise the ability of HVT to protect against Marek’s disease.
Journal ArticleDOI
Location of the structural gene of pseudorabies virus glycoprotein complex gII
Thomas C. Mettenleiter,Noemi Lukacs,Heinz-Jürgen Thiel,Christa Sibilla Schreurs,Hanns-Joachim Rziha +4 more
TL;DR: Using specific antisera and a monoclonal antibody against the glycoprotein complex one single nonglycosylated in vitro translated precursor polypeptide was identified and mapped by hybrid selection of late viral RNA on cloned DNA fragments.
Journal ArticleDOI
Variability of pseudorabies virus glycoprotein I expression.
TL;DR: Viruses resistant to anti-gI antibodies occur spontaneously in vivo and in vitro, which argues against the use of gI as a subunit vaccine.
Journal ArticleDOI
Pseudorabies virus glycoprotein gI: in vitro and in vivo analysis of immunorelevant epitopes.
Walter Fuchs,Hanns-Joachim Rziha,Noemi Lukacs,Ingrid Braunschweiger,Nico Visser,Dieter Lutticken,Christa Sibilla Schreurs,Heinz-J. Thiel,Thomas C. Mettenleiter +8 more
TL;DR: The results show that gI, which is non-essential for virus replication in tissue culture, can induce neutralizing and protective antibodies and the potential suitability of fusion proteins encompassing N-terminal parts of gI as diagnostic tools is demonstrated.
Patent
Vaccine against pseudorabies virus.
Christa Sibilla Schreurs,Thomas C. Mettenleiter,Artur Josef Simon,Noemi Lukacs,Hanns Joachim Rhiza +4 more
TL;DR: The present invention relates to a pseudorabies virus vaccine (PRV) containing a polypeptide GII PRV glycoprotein or fragment thereof, which has shown to be the interaction site PRV neutralizing antibodies.