Showing papers in "Virology in 1986"

TL;DR: The complete nucleotide sequence of the tobacco etch virus (TEV) RNA genome has been determined excepting only the nucleotide(s) present at the extreme 5' terminus, and a function for the large nuclear inclusion protein is suggested by a comparison of the deduced amino acid sequence with a protein data bank.

TL;DR: The Jijoye EBV strain is characterized by a substitution of 1.8 kb in the C-terminal part of the EBNA 2 gene compared to B95-8 or M-ABA virus, which made it possible to construct hybridization probes specific for M- aBA (type A) and JiJoye viruses (type B), which have been used to type the EBV genomes in 38 spontaneously established cell lines.

TL;DR: The complete nucleotide sequence of human papilloma virus type 11 (HPV11) DNA (7931 bp) was determined and shows a high degree of sequence homology to HPV6b.

TL;DR: A WNV mutant, which replicates progeny genome RNA more efficiently than parental WNV, was found to have a 3'-genomic sequence identical to that of its parent virus, indicating that this structure is important for the survival of the virus.

TL;DR: The properties of monoclonal antibody LP11, directed against gH show remarkable similarities to the properties for gD antibodies, which imply functional relatedness between gH and gD of herpes simplex virus.

TL;DR: It is shown that vaccinia virus induces SV40 DNA amplification also in the SV40-transformed Chinese hamster embryo cell line, CO631, and a poxvirus--vaccinia virus--similar to herpes group viruses induces DNA amplification.

TL;DR: The data demonstrate that the coding strategy of the Hantaan virus S RNA is different than those reported for other viruses in this family.

TL;DR: Comparison of sequence homology of structural proteins suggests that dengue virus is more closely related to WN virus than to YF virus or Murray Valley encephalitis virus, and analysis of the extreme 5'- and 3'-terminal nucleotides of the d Dengue virus genome revealed sequences that may be involved in transcription, replication, and packaging of viral RNA.

TL;DR: All VP7-specific monoclonal antibodies (mAb) mediated serotype-specific neutralization, but a VP3-specific mAb was identified that neutralized rotaviruses of three distinct serotypes.

TL;DR: It is concluded that the distribution of hydrophobic regions capable of spanning biological membranes determines the fusogenic nature of the F protein.

TL;DR: The deduced amino acid sequence revealed that the HA protein is a member of typical surface membrane glycoproteins, a basis for a new site suitable for inserting foreign genes in vaccinia virus.

TL;DR: The nucleotide sequence of the 5'-terminal 2469 bases of dengue 2 (Jamaica genotype) virus has been determined and the encoded proteins compared with those of yellow fever and West Nile viruses, which belong to different flavivirus serogroups.

TL;DR: The data indicate that virus-specific structural and nonstructural proteins which are synthesized from a single long ORF accumulate in large amounts in infected cells.

TL;DR: The amino acid changes relative to A/USSR/90/77 are summarised and are consistent with the view that variation in these field strains involves changes largely at the Sb and Ca antigenic sites previously characterised in laboratory mutants of the haemagglutinin of influenza A/PR/8/34.

TL;DR: The results indicate that the heat-induced changes in hemagglutinin which allow fusion activity result in partial denaturation of the molecule, and the changes in structure required for fusion at low pH and normal temperature are specifically restricted.

TL;DR: The deduced amino acid structure of the protein indicates that the only major hydrophobic region of sufficient length to anchor the molecule in membranes is located near the amino terminus.

TL;DR: The data support previous suggestions that actin is involved in virus budding and show that budding itself is possibly the result of a vectorial growth of actin filaments.

TL;DR: Immunoprecipitation and Western blot analysis of total proteins from disrupted HTLV-III virions with the specific antiserum failed to detect the 3'orf protein products, suggesting that they are not a major component of mature virions and may be involved in the intracellular regulation of viral replication.

TL;DR: Alignment of the F0 protein sequences of PF3 with those of Sendai, SV5, and respiratory syncytial virus (RSV) using a matrix that scores both amino acid matches and mismatches provided highly significant statistical evidence that all four proteins are related.

TL;DR: High sequence variability could possibly account for the diversity of defects observed in MV gene expression in SSPE brains and may be a general phenomenon associated with RNA virus persistence.

TL;DR: The genome of varicella-zoster virus (VZV) encodes three major glycoproteins, two of which (gpI and gpII) having been mapped and sequenced, which carry epitopes capable of eliciting neutralizing antibodies.

TL;DR: A novel murine retrovirus complex was derived from the in vivo passage of a molecularly cloned Friend ecotropic helper virus that caused an acute and generalized myeloproliferative disorder in adult mice and exhibits unique biological properties that distinguish it either from the Friend virus complexes or from acutely transforming sarcomatogenic murine Retrovirus.

TL;DR: The 3′ end of the 20-kb genome of the Purdue strain of porcine transmissible gastroenteritis coronavirus was copied into eDNA after priming with oligo(dT) and the double-stranded product was cloned into the PstI site of the pUC9 vector.

TL;DR: The data suggest that TPA enhances the replication of HTLV/III/LAV and these assay systems are shown to be useful for analyzing the induction or suppression of a virus infection by many drugs and other factors in vitro.

TL;DR: The experiments described in this paper were designed to assess the role of the various virus glycoproteins of pseudorabies virus in eliciting the production of neutralizing antibodies during the normal course of infection of swine.

TL;DR: The finding that membrane fusion activity, haemolysis, and changes in haemagglutinin conformation covary with pH and temperature provide support for the role of haematological fusion and are discussed in relation to the stability of its structure.

TL;DR: The sequence of the matrix (M) protein gene and contiguous intergenic regions of the human parainfluenza 3 virus was determined by molecular cloning and appears to be the most highly conserved among the Paramyxoviridae proteins.

TL;DR: A detailed description of the env gene region of EIAV is provided and a number of characteristic features of genomic organization in lentiviruses which contrast with the genomic organization of oncogenic retroviruses are described.

TL;DR: Crosslinking and low temperature studies argue against redistribution of the HA and NA after antibody attachment and indicate that the NA on influenza virus occurs in patches.

TL;DR: The acquired immune deficiency syndrome (AIDS) retrovirus, HTLV-III/LAV, encodes a transacting factor which directly or indirectly stimulates the expression of genes linked to its LTR, and the critical functional domain is narrowed down to a coding sequence of 58 codons.