C
Christina Wei
Researcher at St. George's University
Publications - 21
Citations - 444
Christina Wei is an academic researcher from St. George's University. The author has contributed to research in topics: Diabetes mellitus & Insulin resistance. The author has an hindex of 9, co-authored 18 publications receiving 375 citations. Previous affiliations of Christina Wei include St George's Hospital & Bristol Royal Hospital for Children.
Papers
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Journal ArticleDOI
Saturated fatty acids induce insulin resistance in human podocytes: implications for diabetic nephropathy
Rachel Lennon,Deborah A Pons,Matthew A. Sabin,Christina Wei,Julian P.H. Shield,Richard J M Coward,Jeremy M. Tavaré,Peter W Mathieson,Moin A. Saleem,Gavin I. Welsh +9 more
TL;DR: This is the first study to demonstrate a direct effect of saturated fatty acids on podocyte function and may represent a novel link between systemic insulin resistance and the development of nephropathy.
Journal ArticleDOI
Recent advances in the understanding and management of delayed puberty
Christina Wei,Elizabeth Crowne +1 more
TL;DR: The key clinical question is to distinguish delayed puberty associated with an underlying pathology or hypogonadism from constitutional delay in growth and puberty, which remains challenging as biochemical tests are not always discriminatory.
Journal ArticleDOI
Reduced insulin sensitivity in childhood survivors of haematopoietic stem cell transplantation is associated with lipodystropic and sarcopenic phenotypes
Christina Wei,Christina Wei,Manigandan Thyagiarajan,Linda P. Hunt,Julian P.H. Shield,Julian P.H. Shield,Michael C. Stevens,Elizabeth Crowne,Elizabeth Crowne +8 more
TL;DR: This study characterised body composition using different methodologies and explored associations with reduced insulin sensitivities in a group of ALL survivors treated with/without HSCT/TBI.
Journal ArticleDOI
Abnormal liver function in children with metabolic syndrome from a UK-based obesity clinic
TL;DR: Prevalence of transaminitis is significant in obese children and is associated with components of the metabolic syndrome, and lifestyle-based improvement in BMI SDS offers an effective tool for correcting transamination and should remain the central component of therapy.
Journal ArticleDOI
Reduced beta-cell reserve and pancreatic volume in survivors of childhood acute lymphoblastic leukaemia treated with bone marrow transplantation and total body irradiation.
Christina Wei,Manigandan Thyagiarajan,Linda P. Hunt,Rachel Cox,Karin Bradley,Ruth Elson,Julian P Hamilton-Shield,Michael C. Stevens,Elizabeth Crowne +8 more
TL;DR: This study investigates insulin sensitivity, β‐cell reserve and pancreatic volume in adult survivors of childhood acute lymphoblastic leukaemia (ALL) and examines the mechanism behindaired glucose tolerance and diabetes mellitus.