C
Christine M. Madla
Researcher at University College London
Publications - 27
Citations - 1556
Christine M. Madla is an academic researcher from University College London. The author has contributed to research in topics: Jejunum & Ileum. The author has an hindex of 14, co-authored 24 publications receiving 858 citations.
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Journal ArticleDOI
The mechanisms of pharmacokinetic food-drug interactions - A perspective from the UNGAP group.
Mirko Koziolek,Stefano Alcaro,Patrick Augustijns,Abdul Basit,Michael Grimm,Bart Hens,Caroline L. Hoad,Philipp Jedamzik,Christine M. Madla,Marc Maliepaard,Luca Marciani,Annalisa Maruca,Neil Parrott,Petr Pavek,Christopher J.H. Porter,Christos Reppas,Diana van Riet-Nales,Jari Rubbens,Marina Statelova,Natalie L. Trevaskis,Kateřina Valentová,Maria Vertzoni,Dubravka Vitali Čepo,Maura Corsetti,Maura Corsetti +24 more
TL;DR: In this review of the UNGAP Working group "Food-Drug Interface", the different mechanisms that can lead to pharmacokinetic food-drug interactions are discussed and summarised from different expert perspectives.
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Fabricating 3D printed orally disintegrating printlets using selective laser sintering
Fabrizio Fina,Christine M. Madla,Alvaro Goyanes,Jiaxin Zhang,Simon Gaisford,Abdul Basit,Abdul Basit +6 more
TL;DR: The work reported here is the first to demonstrate the feasibility of SLS 3DP to fabricate printlets with accelerated drug release and orally disintegrating properties, and confirmed that SLS is amenable to the pharmaceutical research of modern medicine manufacture.
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3D printing of drug-loaded gyroid lattices using selective laser sintering.
Fabrizio Fina,Alvaro Goyanes,Christine M. Madla,Atheer Awad,Sarah J. Trenfield,Jia Min Kuek,Pavanesh Patel,Simon Gaisford,Abdul Basit,Abdul Basit +9 more
TL;DR: This work is the first to demonstrate the feasibility of using SLS to achieve customised drug release properties of several polymers, in a swift, cost‐effective manner, avoiding the need to alter the formulation composition.
Journal ArticleDOI
Shaping the future: recent advances of 3D printing in drug delivery and healthcare
Sarah J. Trenfield,Atheer Awad,Christine M. Madla,Grace B. Hatton,Jack Firth,Alvaro Goyanes,Simon Gaisford,Abdul Basit +7 more
TL;DR: The review covers the state of the art of 3D printing in healthcare (covering topics such as dentistry, surgical and bioprinting of patient-specific organs), as well as the potential of recent innovations, such as 4D printing, to shape the future of drug delivery and to improve treatment pathways for patients.
Journal ArticleDOI
Automated therapy preparation of isoleucine formulations using 3D printing for the treatment of MSUD: First single-centre, prospective, crossover study in patients.
Alvaro Goyanes,Alvaro Goyanes,Christine M. Madla,Aysha Umerji,Goretti Duran Piñeiro,José-María Montero,María Jesús Lamas Diaz,Miguel Gonzalez Barcia,Farhan Taherali,Paula Sánchez-Pintos,María-Luz Couce,Simon Gaisford,Abdul Basit,Abdul Basit +13 more
TL;DR: 3D printing is demonstrated for the first time that 3D printing offers a feasible, rapid and automated approach to prepare oral tailored-dose therapies in a hospital setting for the preparation of personalised therapies in paediatric patients suffering from MSUD.