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Christine Perdan Curran
Researcher at Northern Kentucky University
Publications - 12
Citations - 166
Christine Perdan Curran is an academic researcher from Northern Kentucky University. The author has contributed to research in topics: Aryl hydrocarbon receptor & Neurotransmitter receptor. The author has an hindex of 6, co-authored 12 publications receiving 118 citations.
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Taurine, caffeine, and energy drinks: Reviewing the risks to the adolescent brain.
TL;DR: Although the aged or diseased brain might benefit from taurine or caffeine supplementation, it appears that adolescents are not likely to benefit from supplementation and may, in fact, suffer ill effects from chronic ingestion of high doses.
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Incorporating genetics and genomics in risk assessment for inhaled manganese: from data to policy.
TL;DR: Novel components of this risk assessment include an attempt to quantify the range of inter-individual differences using data generated by the Human Genome Project and experimental work to identify genetically based biomarkers of exposure, disease and susceptibility.
Journal ArticleDOI
Comparison of Neurological Function in Males and Females from Two Substrains of C57BL/6 Mice.
Amy Ashworth,Mark E. Bardgett,Jocelyn Phillips Fowler,Helen Garber,Molly S. Griffith,Christine Perdan Curran +5 more
TL;DR: The findings demonstrate the importance of testing both males and females in neurobehavioral studies, and both factors (sex and substrain) must be taken into account when designing developmental neurotoxicology studies.
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AhrdCyp1a2(−/−) mice show increased susceptibility to PCB-induced developmental neurotoxicity
Christine Perdan Curran,Emily Altenhofen,Amy Ashworth,Austin Brown,Cellestine Kamau-Cheggeh,Melinda Curran,Amber Evans,Rikki Floyd,Jocelyn Phillips Fowler,Helen Frances Garber,Breann Hays,Sarah Kraemer,Anna Lang,Andrea Mynhier,Ashton Samuels,Carly Strohmaier +15 more
TL;DR: Results indicate Cyp1a2 genotype is more important in susceptibility to PCB-induced deficits in learning and memory, but Ahr genotype appears more important when assessing acoustic startle-PPI and locomotor activity.
Journal ArticleDOI
Genetic differences in the aryl hydrocarbon receptor and CYP1A2 affect sensitivity to developmental polychlorinated biphenyl exposure in mice: relevance to studies of human neurological disorders
Kelsey Klinefelter,Molly Kromme Hooven,Molly Kromme Hooven,Chloe Bates,Breann T. Colter,Alexandra Dailey,Smitha Krishnan Infante,Izabela Kania-Korwel,Hans-Joachim Lehmler,Alejandro López-Juárez,Clare Pickering Ludwig,Christine Perdan Curran +11 more
TL;DR: The data suggest that the AHR pathway plays a role in developmental PCB neurotoxicity, but there is little evidence that developmental exposure is a risk factor for Parkinson’s disease.