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Christopher J. Murray
Researcher at Pacific Northwest National Laboratory
Publications - 83
Citations - 3359
Christopher J. Murray is an academic researcher from Pacific Northwest National Laboratory. The author has contributed to research in topics: Hanford Site & Vadose zone. The author has an hindex of 23, co-authored 83 publications receiving 2609 citations. Previous affiliations of Christopher J. Murray include Stanford University.
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Quantifying Community Assembly Processes and Identifying Features that Impose Them
James C. Stegen,Xueju Lin,Xueju Lin,James K. Fredrickson,Xingyuan Chen,David W. Kennedy,Christopher J. Murray,Mark L. Rockhold,Allan E. Konopka +8 more
TL;DR: An analytical framework is developed for interrogation of subsurface microbial communities distributed across two geologically distinct formations of the unconfined aquifer underlying the Hanford Site in southeastern Washington State that quantitatively estimate influences of Drift, Selection and Dispersal.
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Microscale to Manufacturing Scale-up of Cell-Free Cytokine Production—A New Approach for Shortening Protein Production Development Timelines
James Zawada,Gang Yin,Alexander R. Steiner,Junhao Yang,Alpana Naresh,Sushmita Mimi Roy,Daniel Gold,Henry Heinsohn,Christopher J. Murray +8 more
TL;DR: It is shown how a fully bioactive protein produced by OCFS from optimized frozen extract can be purified directly using a streamlined purification process that yields a biologically active cytokine, human granulocyte‐macrophage colony‐stimulating factor, produced at titers of 700 mg/L in 10 h.
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Aglycosylated antibodies and antibody fragments produced in a scalable in vitro transcription-translation system
Gang Yin,Eudean D Garces,Junhao Yang,Juan Zhang,Cuong D. Tran,Alexander R. Steiner,Christine Roos,Sunil Bajad,Susan Hudak,Kalyani Penta,James Zawada,Sonia Pollitt,Christopher J. Murray +12 more
TL;DR: The results illustrate how the open nature of the cell-free system can be used as a seamless antibody engineering platform from discovery to preclinical development of aglycosylated monoclonal antibodies and antibody fragments as potential therapeutics.
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Physicochemical Characteristics of the Hyporheic Zone Affect Redd Site Selection by Chum Salmon and Fall Chinook Salmon in the Columbia River
David R. Geist,Timothy P. Hanrahan,Evan V. Arntzen,Geoffrey A. McMichael,Christopher J. Murray,Yi-Ju Chien +5 more
TL;DR: It was found that chum salmon spawned in upwelling water that was significantly warmer than the surrounding river water, and fall chinook salmon constructed redds at downwelling sites, where there was no difference in temperature between the river and its bed.
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Variably saturated flow and multicomponent biogeochemical reactive transport modeling of a uranium bioremediation field experiment.
Steven B. Yabusaki,Yilin Fang,Kenneth H. Williams,Christopher J. Murray,Anderson L. Ward,Richard Dayvault,Scott R. Waichler,Darrell R. Newcomer,Frank A. Spane,Philip E. Long +9 more
TL;DR: Three-dimensional, coupled variably saturated flow and biogeochemical reactive transport modeling of a 2008 in situ uranium bioremediation field experiment is used to better understand the interplay of transport and bio geochemical reactions controlling uranium behavior under pulsed acetate amendment and seasonal water table variation.