Chun Feng

TL;DR: The maternal high-E2 environment in the first trimester is correlated with increased risks of LBW and SGA, and Evaluation of serum E2 before ET should be adopted to reduce the possibility of high E2 exposure to gamete/embryo.

TL;DR: The results indicate that risks of gene mutation may increase in the ART offspring, even though their fathers have normal spermatogenesis and genetic background, and intense attention should be placed on genetic safety in theART children, and the benefits and risks of adopting ART should be balanced gingerly.

TL;DR: The results may provide new insights into the pathophysiological mechanisms of early-onset DOR and larger studies in varying populations may validate the role of GDF9 mutation in young women with DOR.

TL;DR: The present results reveal that abnormal protein profiles are involved in ART placenta and these differentially expressed proteins may be valuable for the evaluation of potential association between ART treatment and offspring outcome.

TL;DR: The global profile of imprinting is stable in children conceived through ART, however, imprinting of a few specific imprinted genes may be vulnerable in a fraction of ART-conceived children.