Claire Bardel

TL;DR: Solid lipid nanoparticles suspensions were shown as efficient as commercial solutions for skin penetration and were non-corrosive while commercial solutions presented a corrosive potential; and would constitute a promising formulation for hair loss treatment.

TL;DR: It is suggested that the BCL11A and HBS1L-MYB loci have a minor effect on HbF level compared to the XmnI QTL in beta-thalassemia intermedia patients.

TL;DR: Under models where the susceptibility to the disease is caused by a single genetic variant, the cladistic test is neither really more powerful to detect an association nor really more efficient to localize the susceptibility site than an individual SNP testing, however, when two interacting sites are responsible for the disease, thecladistic analysis greatly improves the probability to find the two susceptibility sites.

TL;DR: Next-generation sequencing used to characterise breakpoints of balanced chromosomal rearrangements at the molecular level in patients with intellectual disability and/or congenital anomalies suggested that DNA breaks arose randomly and that there was no major influence of repeated elements.

TL;DR: Intergenic rs2242592 appears to be involved in the genetic vulnerability to schizophrenia, whereas the ANKK1 rs1800497 appears to have a modifying rather than causative effect.