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Claire M. B. Holloway
Researcher at University of Toronto
Publications - 54
Citations - 2101
Claire M. B. Holloway is an academic researcher from University of Toronto. The author has contributed to research in topics: Breast cancer & Cancer. The author has an hindex of 17, co-authored 47 publications receiving 1774 citations. Previous affiliations of Claire M. B. Holloway include McGill University Health Centre & Cancer Care Ontario.
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Journal ArticleDOI
Sentinel node biopsy after neoadjuvant chemotherapy in biopsy-proven node-positive breast cancer: the SN FNAC study.
Jean-Francois Boileau,Brigitte Poirier,Mark Basik,Claire M. B. Holloway,Louis Gaboury,Lucas Sideris,Sarkis Meterissian,Angel Arnaout,Muriel Brackstone,David R. McCready,Stephen E. Karp,Isabelle Trop,Andre Lisbona,Frances C. Wright,Rami Younan,Louise Provencher,Erica Patocskai,Atilla Omeroglu,André Robidoux +18 more
TL;DR: It is recommended that SN evaluation with IHC be further evaluated before being included in future guidelines on the use of SNB after NAC in this setting, and a low SNB FNR (8.4%) can be achieved with mandatory use of IHC.
Journal Article
Breast adipose tissue concentrations of polychlorinated biphenyls and other organochlorines and breast cancer risk.
Kristan J. Aronson,Anthony B. Miller,Christy G. Woolcott,Ernest E. Sterns,David R. McCready,Lavina Lickley,Edward B. Fish,George Y. Hiraki,Claire M. B. Holloway,Ted Ross,Wedad Hanna,Sandip SenGupta,Jean-Phillipe Weber +12 more
TL;DR: Clear associations with breast cancer risk were demonstrated in this study for some PCBs measured in breast adipose tissue, including p,p'-1,1-dichloro-2,2-bis(p-chlorophenyl)ethylene.
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Imaging of HER2/neu-positive BT-474 human breast cancer xenografts in athymic mice using 111In-trastuzumab (Herceptin) Fab fragments
Ying Tang,Judy Wang,Deborah A. Scollard,Hridya Mondal,Claire M. B. Holloway,Harriette J. Kahn,Raymond M. Reilly,Raymond M. Reilly +7 more
TL;DR: In-trastuzumab Fab localized specifically in HER2/neu-positive BT-474 human breast cancer xenografts in athymic mice with tumor uptake of 7.7% injected dose (ID)/g and tumor/blood ratio of 25.2+/-1.6 at 72 h postinjection.
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The role of reexcision for positive margins in optimizing local disease control after breast-conserving surgery for cancer.
Dalal Aziz,Ellen Rawlinson,Steven A. Narod,Ping Sun,H. Lavina A. Lickley,David R. McCready,Claire M. B. Holloway +6 more
TL;DR: The data confirm the results of previous studies indicating that young age is an independent predictor of positive margins after lumpectomy for invasive breast cancer and a trend toward a higher local recurrence rate if more than one procedure was required to secure clear margins, although this effect was not independent of other factors.
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Enumeration of circulating tumor cells in the blood of breast cancer patients after filtration enrichment: correlation with disease stage.
Harriette J. Kahn,Anthony Presta,Lu-Ying Yang,John Blondal,Maureen Trudeau,Lavina Lickley,Claire M. B. Holloway,David R. McCready,Daniel Maclean,Alexander Marks,Alexander Marks +10 more
TL;DR: The results support the concept that CTC can be detected and enumerated in peripheral blood and that this minimally invasive assay merits further evaluation as a potential prognostic indicator and marker of disease progression.