C
Clare J. Fowler
Researcher at University College London Hospitals NHS Foundation Trust
Publications - 43
Citations - 2655
Clare J. Fowler is an academic researcher from University College London Hospitals NHS Foundation Trust. The author has contributed to research in topics: Overactive bladder & Urinary bladder. The author has an hindex of 21, co-authored 43 publications receiving 2486 citations. Previous affiliations of Clare J. Fowler include Lund University & Aristotle University of Thessaloniki.
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Journal ArticleDOI
Decreased sensory receptors p2x3 and trpv1 in suburothelial nerve fibers following intradetrusor injections of botulinum toxin for human detrusor overactivity
Apostolos Apostolidis,R Popat,Y. Yiangou,D. Cockayne,A.P.D.W. Ford,J.B. Davis,Prokar Dasgupta,Clare J. Fowler,P. Anand +8 more
TL;DR: Investigation of a possible effect of BoNT/A on human bladder afferent mechanisms by studying the sensory receptors P2X3 and TRPV1 in biopsies from patients with neurogenic or idiopathic DO found decreased levels of sensory receptors may contribute to the clinical effect ofBoNT/B in detrusor overactivity.
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A UK consensus on the management of the bladder in multiple sclerosis
Clare J. Fowler,Jalesh N. Panicker,Marcus J. Drake,C Harris,S C W Harrison,Mike Kirby,M Lucas,N Macleod,J Mangnall,A North,B Porter,Sheilagh Reid,N Russell,K Watkiss,M Wells +14 more
TL;DR: It was agreed that in the majority of cases, successful management could be based on a simple algorithm which includes using reagent sticks to test for urine infection and measurement of the post micturition residual urine volume, in contrast with published guidelines from other countries which recommend cystometry.
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Treatment of erectile dysfunction with sildenafil citrate (Viagra) in parkinsonism due to Parkinson's disease or multiple system atrophy with observations on orthostatic hypotension
TL;DR: Sidenafil citrate (50 mg) is efficacious in the treatment of erectile dysfunction in parkinsonism due to Parkinson's disease or multiple system atrophy; however, it may unmask or exacerbate hypotension in multiple systematrophy.
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Abnormal electromyographic activity of the urethral sphincter, voiding dysfunction and polycystic ovaries: a new syndrome?
Clare J. Fowler,T. J. Christmas,Christopher R. Chapple,Helen Parkhouse,Roger Kirby,H. S. Jacobs +5 more
TL;DR: A speculative hypothesis for the observed association of impaired voiding, abnormal electromyographic activity of the urinary sphincter, and polycystic ovaries is advanced, based on the relative progesterone deficiency that characterises the poly Cystic ovary syndrome.
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Parallel changes in bladder suburothelial vanilloid receptor TRPV1 and pan-neuronal marker PGP9.5 immunoreactivity in patients with neurogenic detrusor overactivity after intravesical resiniferatoxin treatment.
Ciaran Brady,Apostolos Apostolidis,M. Harper,Yiangos Yiangou,A. Beckett,Thomas S. Jacques,Alex Freeman,Francesco Scaravilli,Clare J. Fowler,Praveen Anand +9 more
TL;DR: To compare PGP9.5 and transient receptor potential vanilloid receptor (TRPV1) suburothelial immunoreactivity between controls and patients with spinal neurogenic detrusor overactivity, data are analyzed before and after treatment with intravesical resiniferatoxin.