Clemens Sommer

TL;DR: A new subclinical experimental autoimmune encephalomyelitis model in humanized mice of myelin-induced CNS inflammation by human T cells may allow testing of new human-specific therapeuticals for multiple sclerosis.

TL;DR: The data indicate a dissociation of neuronal survival and dendritic integrity 6 weeks after short-term ischemia usually used for ischemic preconditioning, which is the most sensitive method to detect subtle dendrite changes compared to the classical dendedritic marker molecules MAP2 and MAP1B.

TL;DR: In this article, postischemic down-regulation of hippocampal CB1 receptors, specifically seen after short-term ischemia usually used for preconditioning, may participate in the mechanisms of endogenous post-ischemic neuroprotection, which can be prevented by "preconditioning" with a short ischemic stimulus of 2.5min duration.

TL;DR: IG1R is as an attractive target for the development of new therapy protocols for HGNET-BCOR patients, which may include ceritinib and vinblastine.

TL;DR: The clinical, radiologic, and postmortem findings of a 42-year-old man with intravascular lymphomatosis, who presented with a conus medullaris syndrome followed by progressive, disseminated spinal and cerebral symptoms, are described.