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Conghui Wang
Researcher at Zhejiang University
Publications - 12
Citations - 130
Conghui Wang is an academic researcher from Zhejiang University. The author has contributed to research in topics: Ovarian cancer & Microvesicles. The author has an hindex of 4, co-authored 10 publications receiving 30 citations.
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Journal ArticleDOI
Microenvironment remodeled by tumor and stromal cells elevates fibroblast-derived COL1A1 and facilitates ovarian cancer metastasis.
TL;DR: It is suggested that microenvironment remodeled by tumor cells and stromal cells promotes fibroblasts to secrete COL1A1 and facilitates the metastasis of ovarian cancer, which may provide a new approach for ovarian cancer therapeutics.
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Exosome-mediated transfer of CD44 from high-metastatic ovarian cancer cells promotes migration and invasion of low-metastatic ovarian cancer cells
Shen Xiameng,Conghui Wang,Huihui Zhu,Yaping Wang,Xinyu Wang,Xiaodong Cheng,Wanzhong Ge,Weiguo Lu +7 more
TL;DR: In this paper, the role and mechanisms of tumor-derived exosomes in progression and metastasis of ovarian cancer in vitro were investigated by using differential centrifugation method; the morphology, size and biological markers of exosome were separately defined by transmission electron microscopy, nanoS90 and Western blotting; Trans-well chambers assay was used to assess the ability of migration and invasion of recipient cells uptaking the Exosomes from HO8910PM cells.
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LncRNA SPOCD1-AS from ovarian cancer extracellular vesicles remodels mesothelial cells to promote peritoneal metastasis via interacting with G3BP1.
Conghui Wang,Jiaying Wang,Shen Xiameng,Mingyue Li,Yongfang Yue,Xiaodong Cheng,Weiguo Lu,Xinyu Wang,Xing Xie +8 more
TL;DR: In this article, the authors investigated how long non-coding RNA (lncRNA) SPOCD1-AS from ovarian cancer extracellular vesicles (EVs) remodel mesothelial cells through a mesothel-to-mesenchymal transition (MMT) manner and facilitate peritoneal metastasis.
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Potential of peptide-engineered exosomes with overexpressed miR-92b-3p in anti-angiogenic therapy of ovarian cancer.
Jiaying Wang,Conghui Wang,Yang Li,Mingyue Li,Tingjia Zhu,Zhangjin Shen,Hui Wang,Weiguo Lv,Xinyu Wang,Xiaodong Cheng,Xing Xie +10 more
TL;DR: In this article, the effect and mechanism of exosomal miR-92b-3p from ovarian cancer cells on tumor-associated angiogenesis and the potential of artificially generated exosomes with overexpressed miR92b3p to be used as anti-angiogenic agent was demonstrated.
Journal ArticleDOI
Down-regulation of UTP23 promotes paclitaxel resistance and predicts poorer prognosis in ovarian cancer.
TL;DR: The findings elucidated a previously unknown function for UTP23 in regulating paclitaxel sensitivity and UTP 23 could serve as a potential prognostic predictor for ovarian cancer.