Y
Yang Li
Researcher at Zhejiang University
Publications - 104
Citations - 4415
Yang Li is an academic researcher from Zhejiang University. The author has contributed to research in topics: Gelatin & Electrospinning. The author has an hindex of 32, co-authored 96 publications receiving 3308 citations. Previous affiliations of Yang Li include Qingdao Agricultural University & Sichuan Normal University.
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Journal ArticleDOI
VEGF-B is dispensable for blood vessel growth but critical for their survival, and VEGF-B targeting inhibits pathological angiogenesis
Fan Zhang,Zhongshu Tang,Xu Hou,Johan Lennartsson,Yang Li,Alexander W. Koch,Pierre Scotney,Chunsik Lee,Pachiappan Arjunan,Lijin Dong,Anil Kumar,Tuomas T. Rissanen,Bin Wang,Nobuo Nagai,Pierre Fons,Robert N. Fariss,Yongqing Zhang,Eric F. Wawrousek,Ginger Tansey,James Raber,Guo-Hua Fong,Hao Ding,David A. Greenberg,Kevin G. Becker,Jean-Marc Herbert,Andrew D. Nash,Seppo Ylä-Herttuala,Yihai Cao,Ryan J. Watts,Xuri Li +29 more
TL;DR: This work indicates that the function of VEGF-B in the vascular system is to act as a “survival,” rather than an “angiogenic” factor and that VEGf-B inhibition may offer new therapeutic opportunities to treat neovascular diseases.
Journal ArticleDOI
miR-375 Is Down-Regulated in Squamous Cervical Cancer and Inhibits Cell Migration and Invasion via Targeting Transcription Factor SP1
Fenfen Wang,Yang Li,Jiansong Zhou,Junfen Xu,Chanjuan Peng,Feng Ye,Yuanming Shen,Weiguo Lu,Xiaoyun Wan,Xing Xie +9 more
TL;DR: The findings suggest that down-regulated miR-375 promotes cell malignant behaviors via the target gene SP1 and may consequently contribute to the progression of cervical cancer.
Journal ArticleDOI
Progressive miRNA expression profiles in cervical carcinogenesis and identification of HPV-related target genes for miR-29†
Yang Li,Fenfen Wang,Junfen Xu,Feng Ye,Yuanming Shen,Jiansong Zhou,Weiguo Lu,Xiaoyun Wan,Ding Ma,Xing Xie +9 more
TL;DR: The results suggest that HPVs have oncogenic properties at least in part by reshaping the milieu of cellular miRNAs, although the abnormality of miR‐29 in HPV‐infected cells might be regulated in an indirect way.
Journal ArticleDOI
VEGF-B inhibits apoptosis via VEGFR-1–mediated suppression of the expression of BH3-only protein genes in mice and rats
Yang Li,Fan Zhang,Nobuo Nagai,Zhongshu Tang,Shuihua Zhang,Pierre Scotney,Johan Lennartsson,Chaoyong Zhu,Yi Qu,Changge Fang,Jianyuan Hua,Osamu Matsuo,Guo-Hua Fong,Hao Ding,Yihai Cao,Kevin G. Becker,Andrew D. Nash,Carl-Henrik Heldin,Xuri Li +18 more
TL;DR: It is shown that VEGF-B inhibited the expression of genes encoding the proapoptotic BH3-only proteins and other apoptosis- and cell death-related proteins, including p53 and members of the caspase family, via activation of VEGFR-1, suggesting that the first member of the V EGF family that has a potent antiAPoptotic effect while lacking a general angiogenic activity.
Journal ArticleDOI
microRNAs are biomarkers of oncogenic human papillomavirus infections.
Xiaohong Wang,Hsu Kun Wang,Yang Li,Yang Li,Markus Hafner,Markus Hafner,Nilam Sanjib Banerjee,Shuang Tang,Daniel Briskin,Daniel Briskin,Craig Meyers,Louise T. Chow,Xing Xie,Thomas Tuschl,Thomas Tuschl,Zhi-Ming Zheng +15 more
TL;DR: It is reported in this study that oncogenic human papillomaviruses (HPVs) induce aberrant expression of many cellular miRNAs and that HPV18 infection produces no detectable viral miRNA.