C
Costanzo Moretti
Researcher at University of Rome Tor Vergata
Publications - 72
Citations - 3327
Costanzo Moretti is an academic researcher from University of Rome Tor Vergata. The author has contributed to research in topics: Receptor & Pregnancy. The author has an hindex of 27, co-authored 69 publications receiving 3074 citations. Previous affiliations of Costanzo Moretti include Policlinico Umberto I & Sapienza University of Rome.
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Journal ArticleDOI
Leptin and androgens in male obesity: Evidence for leptin contribution to reduced androgen levels
Andrea M. Isidori,Massimiliano Caprio,Felice Strollo,Costanzo Moretti,Gaetano Frajese,Aldo Isidori,Andrea Fabbri +6 more
TL;DR: Excess of circulating leptin may be an important contributor to the development of reduced androgen levels in male obesity, according to previous in vitro findings.
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Expression of functional leptin receptors in rodent Leydig cells
Massimiliano Caprio,Andrea M. Isidori,Anna R. Carta,Costanzo Moretti,Maria L. Dufau,Andrea Fabbri +5 more
TL;DR: Findings show that leptin has direct, receptor-mediated actions on rodent Leydig cells in culture, at concentrations within the range of obese men, and indicate that leptin action on steroidogenesis occurs downstream of progesterone synthesis.
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Leptin and aging: correlation with endocrine changes in male and female healthy adult populations of different body weights.
Andrea M. Isidori,Felice Strollo,Michele Moré,Massimiliano Caprio,Antonio Aversa,Costanzo Moretti,Gaetano Frajese,G Riondino,Andrea Fabbri +8 more
TL;DR: The data show that in adult humans of different body weight, serum leptin gradually declines during aging; leptin reduction is higher in women than in men, but it is independent from BMI and other age-related endocrine changes.
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Mild thyroid abnormalities and recurrent spontaneous abortion: diagnostic and therapeutical approach.
E. Vaquero,Caterina De Carolis,Herbert Valensise,Carlo Romanini,Natalia Lazzarin,Costanzo Moretti +5 more
TL;DR: Thyroid replacement therapy appears to be more effective than IVIG in preventing a new miscarriage, and this poor obstetrical prognosis seems to be related to an impaired thyroid adaptation to pregnancy.
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Molecular basis of thyrotropin and thyroid hormone action during implantation and early development
Martina Colicchia,Luisa Campagnolo,Enke Baldini,Salvatore Ulisse,Herbert Valensise,Costanzo Moretti +5 more
TL;DR: Based on recent observations, a local action of TH on female reproductive organs and the embryo during implantation appears to be crucial for a successful pregnancy.