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Costas Georgakopoulos

Researcher at Qatar Airways

Publications -  94
Citations -  1948

Costas Georgakopoulos is an academic researcher from Qatar Airways. The author has contributed to research in topics: Mass spectrometry & Metabolite. The author has an hindex of 23, co-authored 94 publications receiving 1694 citations. Previous affiliations of Costas Georgakopoulos include National Technical University of Athens & Olympic Athletic Center of Athens Spiros Louis.

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Another designer steroid: discovery, synthesis, and detection of 'madol' in urine.

TL;DR: A baboon administration study showed that madol and a metabolite are excreted in urine, and a method for rapid screening of urine samples by gas chromatography/mass spectrometry of trimethylsilylated madol was developed.
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Structural characteristics of anabolic androgenic steroids contributing to binding to the androgen receptor and to their anabolic and androgenic activities. Applied modifications in the steroidal structure.

TL;DR: The structural features of steroids necessary for effective binding to the AR and those which contribute to the stipulation of the androgenic and anabolic activities are presented.
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Preventive doping control analysis: liquid and gas chromatography time-of-flight mass spectrometry for detection of designer steroids.

TL;DR: A new combined doping control screening method for the analysis of anabolic steroids in human urine using liquid chromatography/electrospray ionization orthogonal acceleration time-of-flight mass spectrometry (LCoaTOFMS and GCoaTOF MS) has been developed in order to acquire accurate full scan MS data to be used to detect designer steroids.
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Screening in veterinary drug analysis and sports doping control based on full-scan, accurate-mass spectrometry

TL;DR: In this paper, the authors present data from recent applications of gas chromatography with TOF-MS, ultra-high-performance liquid chromatography (LC) with TOO-MS and LC-Orbitrap MS in the screening of European Commission-regulated veterinary drugs and other contaminants in foods, and World Anti-Doping Agency-prohibited substances.
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Preventive doping control screening analysis of prohibited substances in human urine using rapid-resolution liquid chromatography/high-resolution time-of-flight mass spectrometry.

TL;DR: The preventive role of the method was proved by the case where full scan acquisition with accurate mass measurement allowed the retrospective reprocessing of acquired data from past doping control samples for the detection of a designer drug, the stimulant 4-methyl-2-hexanamine, which resulted in re-reporting a number of stored samples as positives for this particular substance, when, initially, they had been reported as negatives.