Journal•ISSN: 0165-9936
Trends in Analytical Chemistry
Elsevier BV
About: Trends in Analytical Chemistry is an academic journal published by Elsevier BV. The journal publishes majorly in the area(s): Chemistry & Mass spectrometry. It has an ISSN identifier of 0165-9936. Over the lifetime, 5491 publications have been published receiving 294246 citations. The journal is also known as: Trends in analytical chemistry & Trends in analytical chemistry (Personal edition).
Papers published on a yearly basis
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TL;DR: This review describes and compares the theoretical and algorithmic foundations of current pre- processing methods plus the qualitative and quantitative consequences of their application to provide NIR users with better end-models through fundamental knowledge on spectral pre-processing.
Abstract: Pre-processing of near-infrared (NIR) spectral data has become an integral part of chemometrics modeling. The objective of the pre-processing is to remove physical phenomena in the spectra in order to improve the subsequent multivariate regression, classification model or exploratory analysis. The most widely used pre-processing techniques can be divided into two categories: scatter-correction methods and spectral derivatives. This review describes and compares the theoretical and algorithmic foundations of current pre-processing methods plus the qualitative and quantitative consequences of their application. The aim is to provide NIR users with better end-models through fundamental knowledge on spectral pre-processing.
1,942 citations
TL;DR: Recent advances in the development of aptamer-based biosensors and bioassay methods, most of which have employed electrochemical, optical and mass-sensitive analytical techniques are summarized.
Abstract: Nucleic-acid aptamers have attracted intense interest and found wide applications in a range of areas. In this review, we summarize recent advances in the development of aptamer-based biosensors and bioassay methods, most of which have employed electrochemical, optical and mass-sensitive analytical techniques. Aptamers exhibit many advantages as recognition elements in biosensing when compared to traditional antibodies. They are small in size, chemically stable and cost effective. More importantly, aptamers offer remarkable flexibility and convenience in the design of their structures, which has led to novel biosensors that have exhibited high sensitivity and selectivity. Recently, the combination of aptamers with novel nanomaterials has significantly improved the performance of aptamer-based sensors, which we also review in this article. In view of the unprecedented advantages brought by aptamers, we expect aptamer-based biosensors to find broad applications in biomedical diagnostics, environmental monitoring and homeland security.
1,192 citations
TL;DR: In this article, a set of 12 principles consisting of known concepts (i.e., reduction in the use of reagents and energy, and elimination of waste, risk, and hazard) together with some new ideas (e.g., the useof natural reagents) are proposed for the future of GAC.
Abstract: The current rapid development of green analytical chemistry (GAC) requires clear, concise guidelines in the form of GAC principles that will be helpful in greening laboratory practices. The existing principles of green chemistry and green engineering need revision for their use in GAC because they do not fully meet the needs of analytical chemistry. In this article we propose a set of 12 principles consisting of known concepts (i.e. reduction in the use of reagents and energy, and elimination of waste, risk and hazard) together with some new ideas (i.e. the use of natural reagents), which will be important for the future of GAC.
1,107 citations
TL;DR: In this review, a new array of analytical methodologies and technologies were introduced related to the analysis of microbial, plant and animal metabolomes (complete collections of all low molecular weight compounds in a cell) and applications are discussed.
Abstract: During the previous decade, a new array of analytical methodologies and technologies were introduced related to the analysis of microbial, plant and animal metabolomes (complete collections of all low molecular weight compounds in a cell). The scientific field of metabolomics was born. In this review, we discuss advances in methodologies and technologies, and outline applications.
1,094 citations
TL;DR: Graphene has proved to be an excellent nanomaterial for applications in electrochemistry as discussed by the authors, and progress in constructing high-performance electrochemical sensors and biosensors.
Abstract: Graphene has proved to be an excellent nanomaterial for applications in electrochemistry. We review progress in constructing high-performance electrochemical sensors and biosensors. We also discuss: different routes for graphene fabrication; graphene-modified electrodes and graphene-composite electrodes for sensing, including those based on ionic liquids; incorporation of biorecognition elements into graphene-based electrodes; and, graphene-supported electrocatalytic nanoparticle-based electrochemical sensors and biosensors.
1,061 citations