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Craig J. Forsyth
Researcher at Ohio State University
Publications - 124
Citations - 3495
Craig J. Forsyth is an academic researcher from Ohio State University. The author has contributed to research in topics: Total synthesis & Okadaic acid. The author has an hindex of 33, co-authored 121 publications receiving 3359 citations. Previous affiliations of Craig J. Forsyth include University of Minnesota & Monash University, Clayton campus.
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Journal ArticleDOI
Total synthesis of halichondrin B and norhalichondrin B
Thomas Daniel Aicher,Keith R. Buszek,Francis G. Fang,Craig J. Forsyth,Sun Ho Jung,Yoshito Kishi,Michael C. Matelich,Paul Michael Scola,Denice M. Spero,Suk Kyoon Yoon +9 more
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Biotherapy of B-cell precursor leukemia by targeting genistein to CD19-associated tyrosine kinases
Fatih M. Uckun,WE Evans,Craig J. Forsyth,Kevin G. Waddick,LT Ahlgren,Lisa M. Chelstrom,A. L. Burkhardt,Joseph B. Bolen,Dorothea E. Myers +8 more
TL;DR: The B43-Gen immunoconjugate bound with high affinity to BCP leukemia cells, selectively inhibited CD19-associated tyrosine kinases, and triggered rapid apoptotic cell death, which led to 100 percent long-term event-free survival from an otherwise invariably fatal leukemia.
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Highly chemoselective oxidation of 1,5-diols to δ-lactones with TEMPO/BAIB
T. Matthew Hansen,Gordon J. Florence,Priscilla Lugo-Mas,Jiehao Chen,Jason N. Abrams,Craig J. Forsyth +5 more
TL;DR: In this paper, the selective oxidative conversion of a variety of highly functionalized 1°, 2°-1,5-diols into the corresponding δ-lactones has been effected simply and efficiently using a reagent system comprised of catalytic 2,2,6, 6,6-tetrmethylpiperidinooxy (TEMPO) and excess bis-acetoxyiodobenzene (BAIB).
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Total Synthesis of Phorboxazole A
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Synthesis and aminoacyl-trna synthetase inhibitory activity of prolyl adenylate analogs
TL;DR: Possible structural differences in or near the active sites of the two enzymes that may be exploited in the future design of compounds that function as species-specific synthetase inhibitors in vivo are indicated.