C
Cristina Varas-Lorenzo
Researcher at Pfizer
Publications - 36
Citations - 2895
Cristina Varas-Lorenzo is an academic researcher from Pfizer. The author has contributed to research in topics: Population & Cohort study. The author has an hindex of 20, co-authored 36 publications receiving 2555 citations. Previous affiliations of Cristina Varas-Lorenzo include Novartis.
Papers
More filters
Journal ArticleDOI
Quality assessment of observational studies in a drug-safety systematic review, comparison of two tools: the Newcastle–Ottawa Scale and the RTI item bank
Andrea V. Margulis,Manel Pladevall,Nuria Riera-Guardia,Cristina Varas-Lorenzo,Lorna Hazell,Nancy D. Berkman,Meera Viswanathan,Susana Perez-Gutthann +7 more
TL;DR: The RTI-IB facilitates a more complete quality assessment than the NOS but is more burdensome; the observed agreement and AC1 statistic in this study were higher than those reported by the RTI’s developers.
Journal ArticleDOI
Nonsteroidal anti-inflammatory drugs and risk of ARF in the general population.
TL;DR: NSAID users had a 3-fold greater risk for developing a first-ever diagnosis of clinical ARF compared with non-NSAIDs users in the general population, and NSAIDs should be used with special caution in patients with hypertension and/or HF.
Journal ArticleDOI
Individual NSAIDs and Upper Gastrointestinal Complications: A Systematic Review and Meta-Analysis of Observational Studies (the SOS Project)
Jordi Castellsague,Nuria Riera-Guardia,Brian Calingaert,Cristina Varas-Lorenzo,Annie Fourrier-Réglat,Federica Nicotra,Miriam C. J. M. Sturkenboom,Susana Perez-Gutthann +7 more
TL;DR: In this article, the authors conducted a systematic review and meta-analysis of observational studies to provide summary relative risks (RR) of upper GI complications associated with the use of individual NSAIDs, including selective cyclooxygenase-2 inhibitors.
Journal ArticleDOI
Nonsteroidal Antiinflammatory Drugs and the Risk of Myocardial Infarction in the General Population
TL;DR: The results do not support the existence of a clinically meaningful interaction between aspirin and NSAIDs, including ibuprofen, including aspirin taken concomitantly.
Journal ArticleDOI
Individual NSAIDs and Upper Gastrointestinal Complications
Jordi Castellsague,Nuria Riera-Guardia,Brian Calingaert,Cristina Varas-Lorenzo,Annie Fourrier-Réglat,Federica Nicotra,Miriam C. J. M. Sturkenboom,Susana Perez-Gutthann +7 more
TL;DR: In this paper, the authors conducted a systematic review and meta-analysis of observational studies to provide summary relative risks (RR) of upper GI complications (UGIC) associated with the use of individual NSAIDs, including selective cyclooxygenase-2 inhibitors.