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Showing papers in "American Journal of Kidney Diseases in 2005"


Journal Article
TL;DR: Cardiovascular Disease in Dialysis Patients Tables: An Overview of Epidemiology of Cardiovascular disease in Children and Work Group Members and Foreword.

1,258 citations


Journal ArticleDOI
TL;DR: In this large cohort of initially healthy men, BMI was associated significantly with increased risk for CKD after 14 years, and strategies to decrease CKD risk might include prevention of overweight and obesity.

430 citations


Journal ArticleDOI
TL;DR: As suggested by estimations obtained using enzymatic serum creatinine measurement, the MDRD equation may be the estimation of choice in elderly patients, whereas the CG estimate is preferable in subjects younger than 65 years Nevertheless, when obesity is present, no reliable estimation can be obtained by using the CG or M DRD formula.

395 citations


Journal ArticleDOI
TL;DR: This cross-sectional cohort study found a high prevalence of calcidiol deficiency and insufficiency in patients with moderate and severe CKD not on dialysis therapy regardless of geographic location.

392 citations


Journal ArticleDOI
TL;DR: The pathogenesis of antiviral drug-induced kidney injury, common nephrotoxic renal syndromes, and strategies for preventing kidney injury are reviewed.

377 citations


Journal ArticleDOI
TL;DR: SF-36 scores were higher in this CKD cohort compared with hemodialysis patients, but lower than in healthy controls, and GFR was not significantly associated with QOL.

367 citations


Journal ArticleDOI
TL;DR: Obesity adults with hypertension have an increased risk for chronic kidney disease, according to the results of the HDFP study.

361 citations


Journal ArticleDOI
TL;DR: Baseline proteinuria is an important risk factor for kidney failure and provides a means to identify patients at greatest risk and proteinuria reduction using an angiotensin receptor-blocking agent, such as irbesartan, should be regarded as an important therapeutic goal in renoprotective strategies.

354 citations


Journal ArticleDOI
TL;DR: This is the first study to show a greater PWV in patients with more advanced CKD from stages 1 to 5, and estimated GFR per 1.73 m2 and systolic BP were the major clinical determinants of arterial stiffness in Patients with CKD independent of conventional risk factors for CVD.

323 citations


Journal ArticleDOI
TL;DR: Estimated GFR and LV mass index have independent effects on both plasma BNP and NT-proBNP concentrations in patients with CKD, and appear to be affected more by declining kidney function, in keeping with the hypothesis that its clearance is predominantly renal.

321 citations


Journal ArticleDOI
TL;DR: Pediatric ARF epidemiological characteristics have changed from primary renal disease to renal involvement secondary to other systemic illness, and longitudinal data from this cohort are underway to determine the long-term sequelae of pediatric ARF.

Journal ArticleDOI
TL;DR: RIFLE classification can improve the ability of such older and established ICU scoring systems as APACHE II and SAPS II in predicting outcome of ICU patients with ARF.

Journal ArticleDOI
TL;DR: NSAID users had a 3-fold greater risk for developing a first-ever diagnosis of clinical ARF compared with non-NSAIDs users in the general population, and NSAIDs should be used with special caution in patients with hypertension and/or HF.

Journal ArticleDOI
TL;DR: Because depression is prevalent, readily diagnosed, and associated with poor outcomes, screening by means of short and valid measurement tools may lead to better diagnosis and treatment of this modifiable risk factor in dialysis patients.

Journal ArticleDOI
TL;DR: Weight gain and both baseline and time-varying obesity may be associated with reduced cardiovascular mortality in MHD patients independent of laboratory surrogates of nutritional status and their changes over time.

Journal ArticleDOI
TL;DR: Whether normalization of plasma bicarbonate concentrations in all patients is desirable therefore requires additional study, but benefits and complications of therapy are addressed, and potential adverse effects are discussed.

Journal ArticleDOI
TL;DR: In the Diabetes Atherosclerosis Intervention Study (DAISI) as discussed by the authors, Fenofibrate significantly reduced the worsening of albumin excretion and improved lipid profiles in patients with type 2 diabetes.

Journal ArticleDOI
TL;DR: Although limitations in physical activity are common among new patients with ESRD in the United States and correlate highly with increased mortality risk, this study shows an association of frequent exercise of up to 4 to 5 times/wk with improved survival.

Journal ArticleDOI
TL;DR: Atrial fibrillation is much more frequent in HD patients than in the general population; age, duration of HD history, presence of some heart diseases, and left atrial dilatation are associated with the arrhythmia.

Journal ArticleDOI
TL;DR: It was found that insulin resistance correlated linearly with decline in renal function, and independent variables related to insulin resistance were bicarbonate and Apo A-1/B levels in patients with CKD.

Journal ArticleDOI
TL;DR: Resistance index at renal biopsy may be useful as one of the prognostic markers for renal outcome in patients followed up for more than 2 years and shows a direct relationship between resistive index and arteriolosclerosis in damaged kidneys.

Journal ArticleDOI
TL;DR: In time-dependent survival analysis, the presence of plasma phosphorus and Ca x P product concentrations greater than K/DOQI targets increased all-cause mortality risk in hemodialysis and peritoneal dialysis patients.

Journal ArticleDOI
TL;DR: Patients with CKD who participated in a multicenter randomized controlled trial of predialysis psychoeducational interventions in the mid-1980s died and no significant survival advantage was evident for early referral to nephrology or the combination of early referral plus predial kidney disease intervention.

Journal ArticleDOI
TL;DR: Almost one quarter of the prevalent hemodialysis population is catheter dependent, and there remain very long delays in achieving a usable permanent access, attributable to delays in both surgical access placement and access maturation.

Journal ArticleDOI
TL;DR: Estimation equations are performed poorly compared with iGFR and are not reliable measures of actual level of function in sick hospitalized patients, especially those with a high BUN/SCr ratio.

Journal ArticleDOI
TL;DR: This is the first study to show an association of periodontal disease with prevalent renal insufficiency, and it is necessary to determine the exact nature of the observed relationship.

Journal ArticleDOI
TL;DR: High positive predictive values indicate that Medicare claims data can be used to accurately identify patients with CKD for study, and the utility of such databases for comparison of patientswith CKD versus lesser degrees of CKD is limited.

Journal ArticleDOI
TL;DR: It is suggested that mesothelial cells that have undergone epithelial-to-mesenchymal transition are the main source of VEGF in PD patients and therefore may be responsible for a high peritoneal transport rate.

Journal ArticleDOI
Li Zuo1, Ying-chun Ma1, Yu-hong Zhou1, Mei Wang1, GuoBin Xu1, Haiyan Wang1 
TL;DR: Results show that in a Chinese population with CKD, MDRD equation 7 and the abbreviated MDRd equation overestimated GFR in patients with CKd stages 4 to 5 and underestimated G FR in those with CK D stage 1, indicating that careful modification of these equations may be necessary in Chinese populations with CKDs.

Journal ArticleDOI
TL;DR: The prevalence of LVH in nondiabetic predialysis patients with CKD is greater than previously reported, and there is evidence that LVH already is present in the early stages of renal disease.