Curt R. Fischer

TL;DR: The characterized library of promoters is used to assess the impact of phosphoenolpyruvate carboxylase levels on growth yield and deoxy-xylulose-P synthase Levels on lycopene production and is illustrated as being generalizable to eukaryotic organisms and thus constitutes an integral platform for functional genomics, synthetic biology, and metabolic engineering endeavors.

TL;DR: This paper examines the prospects for bioproduction of four second-generation biofuels (n-butanol, 2- butanol, terpenoids, or higher lipids) from four feedstocks (sugars and starches, lignocellulosics, syngas, and atmospheric carbon dioxide) and tests seven fast-growing host organisms for tolerance to production stresses.

TL;DR: The detailed characterization of the yeast promoter collection comprising 11 mutants of the strong constitutive Saccharomyces cerevisiae TEF1 promoter is provided, allowing detailed genotype-phenotype characterizations.

TL;DR: Cessation of major outer membrane protein OmpC production and alteration of lipopolysaccharide composition enabled E. coli O157:H7 to escape PP01 infection.

TL;DR: It is shown that N-hydroxy-pipecolic acid metabolites are mobile defense signals produced at the site of bacterial infection and establish and amplify defense in uninfected, distal tissues and suggests that the N-OH-Pip pathway is a promising target for metabolic engineering to enhance disease resistance.