D
D. Bets
Researcher at Merck & Co.
Publications - 10
Citations - 5234
D. Bets is an academic researcher from Merck & Co.. The author has contributed to research in topics: Metformin & Type 2 diabetes. The author has an hindex of 6, co-authored 10 publications receiving 5044 citations.
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Journal ArticleDOI
Cetuximab monotherapy and cetuximab plus irinotecan in irinotecan-refractory metastatic colorectal cancer.
David Cunningham,Yves Humblet,Salvatore Siena,David Khayat,Harry Bleiberg,Armando Santoro,D. Bets,M. Mueser,Andreas Harstrick,Chris Verslype,Ian Chau,Eric Van Cutsem +11 more
TL;DR: Cetuximab has clinically significant activity when given alone or in combination with irinotecan in patients with ir inotecans-refractory colorectal cancer.
Journal ArticleDOI
Effects of short-term treatment with metformin on serum concentrations of homocysteine, folate and vitamin B12 in type 2 diabetes mellitus: a randomized, placebo-controlled trial.
M G Wulffelé,A Kooy,Philippe Lehert,D. Bets,Jeles C. Ogterop,B Borger van der Burg,Ab J.M. Donker,C. D. A. Stehouwer +7 more
TL;DR: Effects of short‐term treatment with metformin on serum concentrations of homocysteine, folate and vitamin B12 in type 2 diabetes mellitus are studied in a randomized, placebo‐controlled trial.
Journal ArticleDOI
Effects of short-term treatment with metformin on markers of endothelial function and inflammatory activity in type 2 diabetes mellitus: a randomized, placebo-controlled trial.
J De Jager,A Kooy,Ph. Lehert,D. Bets,M G Wulffelé,Tom Teerlink,Peter G. Scheffer,Casper G. Schalkwijk,Ab J.M. Donker,Coen D.A. Stehouwer +9 more
TL;DR: Data on this issue are scarce and it is tested, in the setting of a randomized, placebo‐controlled trial, whether metformin can affect endothelial function and low‐grade inflammation.
Journal ArticleDOI
Long-term effects of metformin on endothelial function in type 2 diabetes: a randomized controlled trial
J De Jager,A Kooy,Casper G. Schalkwijk,J. van der Kolk,Philippe Lehert,D. Bets,M G Wulffelé,Ab J.M. Donker,Coen D.A. Stehouwer +8 more
TL;DR: It is investigated whether metformin can improve endothelial function and decrease inflammatory activity, and thereby decrease the risk of atherothrombotic disease.
Journal ArticleDOI
Combined metformin and insulin therapy for patients with type 2 diabetes mellitus.
Huibert Hendrik Ponssen,Jan Willem Frederik Elte,Philippe Lehert,Jan Pieter Schouten,D. Bets +4 more
TL;DR: Combination therapy with metformin and insulin improves glycemic control and reduces insulin requirements.