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D. Chase

Researcher at University of Southampton

Publications -  20
Citations -  561

D. Chase is an academic researcher from University of Southampton. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 12, co-authored 15 publications receiving 537 citations.

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Clinical effectiveness and cost-effectiveness of growth hormone in children: a systematic review and economic evaluation.

TL;DR: Results suggest that the effects of GH on short-term growth velocity (at 1 year) can range from no improvement to approximately 1 standard deviation above the normal growth velocity for children of the same age.
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Practical tools and methods for health technology assessment in Europe: structures, methodologies, and tools developed by the European Network for Health Technology Assessment, EUnetHTA.

TL;DR: The practical methods and tools to support transnational Health Technology Assessment that were developed and pilot tested by the EUnetHTA Collaboration provide high-quality information and methodological frameworks for HTA that facilitate preparation of HTA documentation, and sharing of information in and across national or regional systems.
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A review of the evidence on the effects and costs of implantable cardioverter defibrillator therapy in different patient groups, and modelling of cost-effectiveness and cost-utility for these groups in a UK context.

TL;DR: The multiple sources of routine data available provide an imperfect picture of the need for and use of ICDs, and a Markov model combined UK patient data with data from published randomised controlled trials (RCTs) to estimate incremental costs per life- year or quality-adjusted life-year (QALY) gained was found.
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Growth hormone replacement in adults and bone mineral density: a systematic review and meta‐analysis

TL;DR: A systematic review of randomized trials that compared GH to no active treatment, with BMD as an outcome, found that the effect of GH replacement on bone mineral density (BMD) in adults with GH deficiency (GHD) is uncertain.
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The health technology assessment adaptation toolkit: description and use.

TL;DR: The adaptation toolkit is a collection of resources that help the user assess whether data and information in existing HTA reports should and could be adapted for their own setting, and is designed for the adaptation of evidence synthesis rather than primary research.