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D.D.W. Cornelison

Researcher at University of Missouri

Publications -  34
Citations -  2392

D.D.W. Cornelison is an academic researcher from University of Missouri. The author has contributed to research in topics: Myocyte & Skeletal muscle. The author has an hindex of 14, co-authored 26 publications receiving 2185 citations. Previous affiliations of D.D.W. Cornelison include California Institute of Technology.

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Single-Cell Analysis of Regulatory Gene Expression in Quiescent and Activated Mouse Skeletal Muscle Satellite Cells

TL;DR: C-met receptor is present beneath the basal lamina on presumptive satellite cells in intact muscle and that c-met mRNA and protein are expressed by all myofiber-associated satellite cells from the time of explant through the course of activation, proliferation, and differentiation.
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MyoD(-/-) satellite cells in single-fiber culture are differentiation defective and MRF4 deficient.

TL;DR: Examination of adult muscle fibers and their associated satellite cells in single myofiber cultures suggests that activated MyoD(-/-) satellite cells assume a phenotype that resembles in some ways a developmentally "stalled" cell compared to wildtype.
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Syndecan-4-Expressing Muscle Progenitor Cells in the SP Engraft as Satellite Cells during Muscle Regeneration

TL;DR: It is proposed that this subset of SP cells (satellite-SP cells), characterized by ABCG2, Syndecan-4, and Pax7 expression, constitutes a self-renewing muscle stem cell capable of generating both satellite cells and their myonuclear progeny in vivo.
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3D Timelapse Analysis of Muscle Satellite Cell Motility

TL;DR: Primary satellite cells are significantly more motile than myoblast cell lines, and that adhesion to laminin promotes primary cell motility more than fourfold over other substrates, suggesting that satellite cell migration in vivo may be more extensive than currently thought, and could be regulated by combinations of signals.