On the function and mechanism of action of peroxidases

Synthesis, structure, and bonding in polyiodide and metal iodide-iodine systems.

As a result of the adaptation of life to an aerobic environment, nature has evolved a panoply of metalloproteins for oxidative metabolism and protection against reactive oxygen species. Despite the diverse structures and functions of these proteins, they share common mechanistic grounds. An open-shell transition metal like iron or copper is employed to interact with O2 and its derived intermediates such as hydrogen peroxide to afford a variety of metal–oxygen intermediates. These reactive intermediates, including metal-superoxo, -(hydro)peroxo, and high-valent metal–oxo species, are the basis for the various biological functions of O2-utilizing metalloproteins. Collectively, these processes are called oxygen activation. Much of our understanding of the reactivity of these reactive intermediates has come from the study of heme-containing proteins and related metalloporphyrin compounds. These studies not only have deepened our understanding of various functions of heme proteins, such as O2 storage and trans...

Oxygen Activation and Radical Transformations in Heme Proteins and Metalloporphyrins

Publisher Summary This chapter describes the various aspects of the vibrational spectra of carbohydrates. Vibrational spectroscopy is one of the techniques most adapted techniques for the study of hydrogen bonding, which is the indicator of molecular interaction in the aqueous solutions of sugars. A polyatomic molecule, such as sugar, may be regarded as a system of masses joined by bonds having spring-like properties. The vibration of each of the masses (atoms) can be resolved into components parallel to the x, y, and z axis of a Cartesian system of coordinates. The harmonic approximation is applied in which any motion of the molecule is resolved in a sum of displacements parallel to the Cartesian coordinates and these are called “fundamental, normal modes of vibration.” The analysis of crystallographic results shows the important role played by anomeric center in the structure of sugars. Infrared dichroism in polysaccharides was applied to obtain information on the orientation of chemical groups in the crystalline structure. The computational calculation of the frequencies of carbohydrates' vibration is also elaborated in the chapter.

Vibrational spectra of carbohydrates.

Linear Polyene Electronic Structure and Potential Surfaces

Vibrational spectra of some carotenoids and related linear polyenes. Raman spectroscopic study

The Valence and Spin State of Iron in Oxyhemoglobin as Inferred from Resonance Raman Spectroscopy

Raman spectra of Schiff bases of retinal (models of visual photoreceptors).

Excitation profiles of laser Raman spectra in the resonance region of two carotenoid pigments in solution

Raman spectra of dilute solutions of some steroisomers of vitamin A type molecules

D. Gill

Papers

Vibrational spectra of some carotenoids and related linear polyenes. Raman spectroscopic study

The Valence and Spin State of Iron in Oxyhemoglobin as Inferred from Resonance Raman Spectroscopy

Raman spectra of Schiff bases of retinal (models of visual photoreceptors).

Excitation profiles of laser Raman spectra in the resonance region of two carotenoid pigments in solution

Raman spectra of dilute solutions of some steroisomers of vitamin A type molecules