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D. S. Gill

Researcher at Royal Free Hospital

Publications -  18
Citations -  627

D. S. Gill is an academic researcher from Royal Free Hospital. The author has contributed to research in topics: Histamine & Osteocalcin. The author has an hindex of 13, co-authored 18 publications receiving 606 citations.

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Intraplatelet serotonin in patients with diabetes mellitus and peripheral vascular disease

TL;DR: It is established that NIDDM and PVD patients have significantly (P < 0·002) greater plasma 5‐HT concentrations than controls and this increase in plasma 5-HT may contribute to the pathogenesis of atherosclerosis and vasospasm.
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Rickets in Nigerian children: a consequence of calcium malnutrition

TL;DR: Rickets in Nigerian children is not due to vitamin D deficiency, but to a lack of calcium, and this observation has implications regarding the pathogenesis, treatment, and prevention of rickets/osteomalacia in Nigeria and possibly other African and tropical countries.
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Impaired carboxylation of osteocalcin in warfarin-treated patients.

TL;DR: Osteocalcin carboxylation in humans is a vitamin K-dependent process and that circulating osteocalcin is structurally altered by warfarin administration, which has pathophysiological implications for the fetalwarfarin embryopathy syndrome, bone disease associated with chronic liver diseases, and possibly for osteoporosis.
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Hyperparathyroidism and Low Serum Osteocalcin Despite Vitamin D Replacement in Primary Biliary Cirrhosis

TL;DR: Results indicate that PTH concentrations are frequently elevated in PBC patients despite adequate vitamin D supplementation and normal or even supranormal plasma calcium concentrations, and suggest that vitamin D deficiency and secondary hyperparathyroidism in such patients probably occur much earlier in the natural history of this disease than is currently realized.
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Plasma histamine concentrations are elevated in patients with diabetes mellitus and peripheral vascular disease.

TL;DR: Plasma histamine is elevated in diabetics and in patients with peripheral vascular disease and that platelet and leucocyte histamine content is increased in the latter, which may contribute to the pathogenesis of increased endothelial permeability in diabetes and to the Pathogenesis of intimal damage in atherosclerosis.