D
D. Y. Liu
Researcher at Royal Women's Hospital
Publications - 8
Citations - 640
D. Y. Liu is an academic researcher from Royal Women's Hospital. The author has contributed to research in topics: Sperm & Zona pellucida. The author has an hindex of 7, co-authored 8 publications receiving 628 citations. Previous affiliations of D. Y. Liu include University of Melbourne.
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Journal ArticleDOI
Relationship between sperm motility assessed with the Hamilton-Thorn motility analyzer and fertilization rates in vitro.
TL;DR: Only the diagnoses of male infertility and tubal disease, linearity in semen, and the percentage of motile spermatozoa with average path velocities between 10 and 20 microns/s in insemination medium were significantly related to in vitro fertilization rates.
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Morphology of spermatozoa bound to the zona pellucida of human oocytes that failed to fertilize in vitro.
D. Y. Liu,H. W. G. Baker +1 more
TL;DR: Logistic regression analysis showed that the diagnosis of tubal infertility and the rate of binding of spermatozoa with normal morphology to the ZP were positively related to fertilization rates in vitro while the rateof binding of semen quality-dependent spermatozoon head dimensions and the ratio of length to width in the insemination medium were positively correlated.
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The proportion of human sperm with poor morphology but normal intact acrosomes detected with pisum sativum agglutinin correlates with fertilization in vitro
D. Y. Liu,H.W. Gordon Baker +1 more
TL;DR: Assessment of acrosomes may be of clinical value for predicting the fertility of men with poor sperm morphology, and was the only significant factor related to fertilization rate in the logistic regression analysis.
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Inducing the human acrosome reaction with a calcium ionophore A23187 decreases sperm-zona pellucida binding with oocytes that failed to fertilize in vitro.
D. Y. Liu,H. W. G. Baker +1 more
TL;DR: The sperm-ZP binding ratio of test to control spermatozoa was significantly decreased and the sperm-oolemma binding ratio was significantly increased with A23187 treatment, suggesting that acrosome-reacted spermatozosa do not bind to the human ZP.
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Inhibition of human sperm-zona pellucida and sperm-oolemma binding by antisperm antibodies
TL;DR: The results of this preliminary investigation suggest that antisperm antibodies interfere predominantly with sperm-zona pellucida binding, and implies that the antibody-mediated inhibition of capacitation, acrosome reaction, or oolemma binding may not be major causes of failed fertilization with sperm autoimmunity.