Daici Chen

TL;DR: The Biological General Repository for Interaction Datasets (BioGRID) is an open access archive of genetic and protein interactions that are curated from the primary biomedical literature for all major model organism species.

TL;DR: The BioGRID architecture has been improved to support a broader range of interaction and post-translational modification types, to allow the representation of more complex multi-gene/protein interactions, to account for cellular phenotypes through structured ontologies, to expedite curation through semi-automated text-mining approaches, and to enhance curation quality control.

TL;DR: The Biological General Repository for Interaction Datasets (BioGRID) is a freely available public database that provides the biological and biomedical research communities with curated protein and genetic interaction data.

TL;DR: This protocol describes how to use the BioGRID website to query genetic or protein interactions for any gene of interest, how to visualize the associated interactions using an embedded interactive network viewer, and how to download data files for either selected interactions or the entire Bio GRID interaction data set.

TL;DR: The findings indicated that TSG-6 overexpression in CRC cells could promote cancer metastasis in both an autocrine and paracrine manner, and targeting TSg-6 might be a potential therapeutic strategy for the treatment of metastatic CRC.