Dan Chen

TL;DR: The data suggest that the reconstruction based on heterogeneous mouse model is more accurate in localization and quantification than the homogeneity mouse model with appropriate optical parameters and that BLT allows super-early tumor detection in vivo based on tomographic reconstruction of heterogeneous mice model signal.

TL;DR: In this article, two merocyanine dyes, each with an isoxazolone nucleus, were synthesized and characterized by NMR, IR, UV-Vis spectroscopy, elemental analyses and single X-ray diffraction.

TL;DR: Excision and incision model tests results indicated that the EA fraction of A. cantoniensis showed a significant wound healing capacity at a concentration of 5% (v/w) (p < 0.01) as observed by the increased wound contraction, decreased epithelialization time, and increased hydroxyproline content compared to the ones of the controls.

TL;DR: The photo-triggered one-spot reaction can give a stable crosslinker in a biocompatible manner for bioconjugation with nanoparticles and produce a fluorescent group that is suitable for imaging in vivo.

TL;DR: A novel and simple one-step synthetic method for producing monocarboxylate near-infrared cyanine dyes that may offer the advantages of NIR apoptosis imaging probes for non-invasive tumor imaging and should provide the application for targeted drug delivery and the evaluation of therapeutic efficacy.