D
Dan Madularu
Researcher at Northeastern University
Publications - 36
Citations - 351
Dan Madularu is an academic researcher from Northeastern University. The author has contributed to research in topics: Medicine & Estrogen. The author has an hindex of 10, co-authored 30 publications receiving 227 citations. Previous affiliations of Dan Madularu include McGill University & Douglas Mental Health University Institute.
Papers
More filters
Journal ArticleDOI
Functional magnetic resonance imaging in awake transgenic fragile X rats: evidence of dysregulation in reward processing in the mesolimbic/habenular neural circuit
William M. Kenkel,Jason R. Yee,Jason R. Yee,Kelsey Moore,Dan Madularu,Praveen Kulkarni,Kevin M. Gamber,Mark Nedelman,Craig F. Ferris +8 more
TL;DR: Data speak to an altered processing of this highly salient novel odor in the FX phenotype and lend further support to the notion that altered reward systems in the brain may contribute to fragile X syndrome symptomology.
Journal ArticleDOI
A non-invasive restraining system for awake mouse imaging
Dan Madularu,Dan Madularu,Axel Mathieu,Chathura Kumaragamage,Chathura Kumaragamage,Lauren M. Reynolds,Jamie Near,Cecilia Flores,M. Natasha Rajah,M. Natasha Rajah +9 more
TL;DR: A novel mouse restraining system that is compatible with a range of commercially-available coils, and allows for the pairing of neuroimaging with other established techniques involving intracranial cannulation (i.e. microinfusion and optogenetics).
Journal ArticleDOI
Estrogen potentiates the behavioral and nucleus accumbens dopamine response to continuous haloperidol treatment in female rats
TL;DR: The data suggest that estradiol levels affect both the behavioral and the dopamine responses to chronic antipsychotic treatment, as well as the effects of chronic haloperidol in reducing dopaminergic release in sensitized rats.
Journal ArticleDOI
BOLD Imaging in Awake Wild-Type and Mu-Opioid Receptor Knock-Out Mice Reveals On-Target Activation Maps in Response to Oxycodone
Kelsey Moore,Dan Madularu,Sade Iriah,Jason R. Yee,Praveen Kulkarni,Emmanuel Darcq,Brigitte L. Kieffer,Craig F. Ferris +7 more
TL;DR: Comparison of WT and MuKO mutant mice reveals both on-target and off-target activation events, and set an OXY brain signature that should, in the future, be compared to other μ opioid agonists.
Journal ArticleDOI
Intra-accumbens injection of a dopamine aptamer abates MK-801-induced cognitive dysfunction in a model of schizophrenia.
TL;DR: Injection of the dopamine aptamer reversed thisMK-801-induced elevation in lever pressing to levels as seen in rats not treated with MK-801, demonstrating the in vivo utility of DNA aptamers as tools to investigate neurobiological processes in preclinical animal models of mental health disease.