D
Dan Yuan
Researcher at Brandeis University
Publications - 25
Citations - 1253
Dan Yuan is an academic researcher from Brandeis University. The author has contributed to research in topics: Medicine & Chemistry. The author has an hindex of 12, co-authored 19 publications receiving 1049 citations.
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Journal ArticleDOI
Imaging enzyme-triggered self-assembly of small molecules inside live cells.
TL;DR: A method to image enzyme-triggered self-assembly of small molecules inside live cells and explores supramolecular chemistry inside cells and may lead to new insights, processes, or materials at the interface of chemistry and biology.
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Pericellular Hydrogel/Nanonets Inhibit Cancer Cells†
TL;DR: Pericellular hydrogel/nanonets of small molecules to exhibit distinct functions illustrates a fundamentally new way to engineer molecular assemblies spatiotemporally in cellular microenvironment for inhibiting cancer cell growth and even metastasis.
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Enzyme-Instructed Intracellular Molecular Self-Assembly to Boost Activity of Cisplatin against Drug-Resistant Ovarian Cancer Cells.
Jie Li,Yi Kuang,Junfeng Shi,Jie Zhou,Jamie E. Medina,Rong Zhou,Dan Yuan,Cuihong Yang,Huaimin Wang,Zhimou Yang,Jianfeng Liu,Daniela M. Dinulescu,Bing Xu +12 more
TL;DR: The use of enzyme-instructed self-assembly (EISA) to generate intracellular supramolecular assemblies that drastically boost the activity of cisplatin against drug-resistant ovarian cancer cells are shown.
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d-Amino Acids Modulate the Cellular Response of Enzymatic-Instructed Supramolecular Nanofibers of Small Peptides
TL;DR: A new way for tailoring the properties of supramolecular assemblies is illustrated, and new insights are provided to answering the fundamental question of how mammalian cells respond to enzymatic formation of nanoscale supramolescular assemblies (e.g., nanofibers) of d-peptides.
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Mixing Biomimetic Heterodimers of Nucleopeptides to Generate Biocompatible and Biostable Supramolecular Hydrogels
TL;DR: This work illustrates a new and rational approach to create soft biomaterials by a supramolecular hydrogelation triggered by mixing heterodimeric nucleopeptides that exhibit excellent proteolytic resistance against proteinase K.