D
Dana Bezalel
Researcher at Weizmann Institute of Science
Publications - 2
Citations - 531
Dana Bezalel is an academic researcher from Weizmann Institute of Science. The author has contributed to research in topics: Promoter & Gene. The author has an hindex of 2, co-authored 2 publications receiving 420 citations.
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Journal ArticleDOI
Aging-induced type I interferon response at the choroid plexus negatively affects brain function
Kuti Baruch,Aleksandra Deczkowska,Eyal David,Joseph M. Castellano,Omer Miller,Alexander Kertser,Tamara Berkutzki,Zohar Barnett-Itzhaki,Dana Bezalel,Tony Wyss-Coray,Ido Amit,Michal Schwartz +11 more
TL;DR: Using multiorgan genome-wide analysis of aged mice, it is found that the choroid plexus, an interface between the brain and the circulation, shows a type I interferon (IFN-I)–dependent gene expression profile that was also found in aged human brains.
Journal ArticleDOI
On the relation between promoter divergence and gene expression evolution
TL;DR: It is shown that most previously identified differences in transcription factor (TF)‐binding sequences of yeasts and mammals have no detectable effect on gene expression, suggesting that compensatory mechanisms allow promoters to rapidly evolve while maintaining a stabilized expression pattern.