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Adina Weinberger
Researcher at Weizmann Institute of Science
Publications - 62
Citations - 10515
Adina Weinberger is an academic researcher from Weizmann Institute of Science. The author has contributed to research in topics: Microbiome & Promoter. The author has an hindex of 30, co-authored 52 publications receiving 7169 citations.
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Journal ArticleDOI
Personalized Nutrition by Prediction of Glycemic Responses
David Zeevi,Tal Korem,Niv Zmora,Niv Zmora,David Israeli,Daphna Rothschild,Adina Weinberger,Orly Ben-Yacov,Dar Lador,Tali Avnit-Sagi,Maya Lotan-Pompan,Jotham Suez,Jemal Ali Mahdi,Elad Matot,Gal Malka,Noa Kosower,Michal Rein,Gili Zilberman-Schapira,Lenka Dohnalová,Meirav Pevsner-Fischer,Rony Bikovsky,Zamir Halpern,Eran Elinav,Eran Segal +23 more
TL;DR: A machine-learning algorithm is devised that integrates blood parameters, dietary habits, anthropometrics, physical activity, and gut microbiota measured in an 800-person cohort and shows that it accurately predicts personalized postprandial glycemic response to real-life meals, and a blinded randomized controlled dietary intervention based on this algorithm resulted in significantly lower postpr andial responses and consistent alterations to gut microbiota configuration.
Journal ArticleDOI
Environment dominates over host genetics in shaping human gut microbiota
Daphna Rothschild,Omer Weissbrod,Elad Barkan,Alexander Kurilshikov,Tal Korem,David Zeevi,Paul I. Costea,Anastasia Godneva,Iris N. Kalka,Noam Bar,Smadar Shilo,Dar Lador,Arnau Vich Vila,Niv Zmora,Niv Zmora,Meirav Pevsner-Fischer,David Israeli,Noa Kosower,Gal Malka,Bat Chen Wolf,Tali Avnit-Sagi,Maya Lotan-Pompan,Adina Weinberger,Zamir Halpern,Shai Carmi,Jingyuan Fu,Cisca Wijmenga,Cisca Wijmenga,Alexandra Zhernakova,Eran Elinav,Eran Segal +30 more
TL;DR: Genotype and microbiome data from 1,046 healthy individuals with several distinct ancestral origins who share a relatively common environment are examined, and it is demonstrated that the gut microbiome is not significantly associated with genetic ancestry, and that host genetics have a minor role in determining microbiome composition.
Journal ArticleDOI
Artificial sweeteners induce glucose intolerance by altering the gut microbiota
Jotham Suez,Tal Korem,David Zeevi,Gili Zilberman-Schapira,Christoph A. Thaiss,Ori Maza,David Israeli,Niv Zmora,Shlomit Gilad,Adina Weinberger,Yael Kuperman,Alon Harmelin,Ilana Kolodkin-Gal,Hagit Shapiro,Zamir Halpern,Eran Segal,Eran Elinav +16 more
TL;DR: It is demonstrated that consumption of commonly used NAS formulations drives the development of glucose intolerance through induction of compositional and functional alterations to the intestinal microbiota, thereby calling for a reassessment of massive NAS usage.
Journal ArticleDOI
The human tumor microbiome is composed of tumor type–specific intracellular bacteria
Deborah Nejman,Ilana Livyatan,Garold Fuks,Nancy Gavert,Yaara Zwang,Leore T. Geller,Aviva Rotter-Maskowitz,Roi Weiser,Roi Weiser,Giuseppe Mallel,Elinor Gigi,Arnon Meltser,Gavin M. Douglas,Iris Kamer,Vancheswaran Gopalakrishnan,Tali Dadosh,Smadar Levin-Zaidman,Sofia Avnet,Tehila Atlan,Zachary A. Cooper,Reetakshi Arora,Alexandria P. Cogdill,Abdul Wadud Khan,Gabriel Ologun,Yuval Bussi,Adina Weinberger,Maya Lotan-Pompan,Ofra Golani,Gili Perry,Merav Rokah,Keren Bahar-Shany,Elisa A. Rozeman,Christian U. Blank,Anat Ronai,Ron Shaoul,Amnon Amit,Amnon Amit,Tatiana Dorfman,Ran Kremer,Zvi R. Cohen,Zvi R. Cohen,Sagi Harnof,Sagi Harnof,Tali Siegal,Einav Yehuda-Shnaidman,Einav Nili Gal-Yam,Hagit Shapira,Nicola Baldini,Morgan G. I. Langille,Alon Ben-Nun,Alon Ben-Nun,Bella Kaufman,Bella Kaufman,Aviram Nissan,Talia Golan,Talia Golan,Maya Dadiani,Keren Levanon,Keren Levanon,Jair Bar,Jair Bar,Shlomit Yust-Katz,Shlomit Yust-Katz,Iris Barshack,Iris Barshack,Daniel S. Peeper,Dan J. Raz,Eran Segal,Jennifer A. Wargo,Judith Sandbank,Noam Shental,Ravid Straussman +71 more
TL;DR: A comprehensive analysis of the tumor microbiome was undertaken, studying 1526 tumors and their adjacent normal tissues across seven cancer types, finding that each tumor type has a distinct microbiome composition and that breast cancer has a particularly rich and diverse microbiome.
Journal ArticleDOI
Inferring gene regulatory logic from high-throughput measurements of thousands of systematically designed promoters
Eilon Sharon,Yael Kalma,Ayala Sharp,Tali Raveh-Sadka,Michal Levo,Danny Zeevi,Leeat Keren,Zohar Yakhini,Zohar Yakhini,Adina Weinberger,Eran Segal +10 more
TL;DR: A method for obtaining parallel, highly accurate gene expression measurements from thousands of designed promoters is devised and applied to measure the effect of systematic changes in the location, number, orientation, affinity and organization of transcription-factor binding sites and nucleosome-disfavoring sequences.