D
Dana Olzeski
Researcher at Washington University in St. Louis
Publications - 2
Citations - 332
Dana Olzeski is an academic researcher from Washington University in St. Louis. The author has contributed to research in topics: Oxidative stress & Oxysterol. The author has an hindex of 2, co-authored 2 publications receiving 310 citations.
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Journal ArticleDOI
Cholesterol Oxidation Products Are Sensitive and Specific Blood-Based Biomarkers for Niemann-Pick C1 Disease
Forbes D. Porter,David E. Scherrer,Michael H. Lanier,S. Joshua Langmade,Vasumathi Molugu,Sarah E. Gale,Dana Olzeski,Rohini Sidhu,Dennis J. Dietzen,Rao Fu,Christopher A. Wassif,Nicole M. Yanjanin,Steven P. Marso,John A. House,Charles H. Vite,Jean E. Schaffer,Daniel S. Ory +16 more
TL;DR: Blood concentrations of two related oxysterols molecules were almost 10 times higher in Niemann-Pick C1 patients than in age-matched healthy controls or those with other diseases such as atherosclerosis or diabetes, suggesting that the two oxysterol molecules are accurate diagnostic markers of early clinical disease and can be used not only to monitor disease progression but also to demonstrate drug efficacy.
Journal ArticleDOI
99. Cholesterol oxidation products are sensitive and specific blood-based biomarkers for Niemann–Pick C1 disease
Daniel S. Ory,Forbes D. Porter,David E. Scherrer,Michael H. Lanier,Stephen J. Langmade,Vasumathi Molugu,Sarah E. Gale,Dana Olzeski,Rohini Sidhu,Christopher A. Wassif,Nicole M. Yanjanin,Jean E. Schaffer +11 more