(1963). Periodontal Disease in Pregnancy I. Prevalence and Severity. Acta Odontologica Scandinavica: Vol. 21, No. 6, pp. 533-551.

Periodontal disease in pregnancy. i. prevalence and severity.

Lichen planus (LP) is a common oral disorder which may represent the manifestation of a mucosal reaction to a variety of aetiological factors. Of the many immunological changes described in LP several may be epiphenomena although a cell-mediated immune response to unidentified antigens or antigenic changes clearly is involved. Associations with drugs or systemic disorders are well-defined in some patients but may, in others, be aleatoric. Finally, the prognosis of oral LP not only differs from that of cutaneous LP but there is little doubt that in a few instances LP is a premalignant condition.

Lichen planus. review and update on pathogenesis

The dynamics of pulp inflammation: correlations between diagnostic data and actual histologic findings in the pulp.

Clinical studies have shown that oral tissues can be affected by pregnancy. Pregnancy-related changes are most frequent and most marked in gingival tissue. Pregnancy does not cause gingivitis, but ...

Effect of pregnancy on periodontal and dental health

Clinical features of burning mouth syndrome

Glossodynia: A Study of Idiopathic Orolingual Pain

THIS study was undertaken for the purpose of comparing the relative merits of oral and vaginal epithelial smears in an attempt to simplify or supplement the clinical method of appraising the endocrine changes during the ovarian cycle in women. Vaginal smears have been shown to be useful in studying the menstrual cycle, and it was felt that similar changes might be reflected in the oral mucosa since the latter possesses certain features in common with the vaginal mucosa, when examined histologically. For example, both areas may simultaneously present signs of leukoplakia, lichen planus, ulcers, and other diseases. On the other hand, there are differences. The oral mucosa is composed of more layers of cells than the resting vaginal mucosa; the outer basal cell layer and the intermediate and superficial cell layers of the vagina do not have exact counterparts in the oral epithelium; the cornified cells, when present, comprise the most superficial layer in the oral epithelium while in the vaginal epithelium t...

A comparison of oral and vaginal epithelial smears.

Pregnancy gingivitis: History, classification, etiology

We recently reported observations (8) on the gums of a group of 416 pregnant women, most of whom had one of the four recognized forms of \"pregnancy gingivitis.\" Although these changes are usually designated by this name, we pointed out that similar pathological conditions are also seen in states other than pregnancy-during menstruation, and in boys and girls at about the age of puberty. Because this condition occurs during periods usually associated with hormonal change, we hoped to gain an insight into its etiology by attempting to reproduce like lesions in experimental animals. Our observations included the gums of monkeys being treated with an extract of pregnancy urine prepared by precipitation with alcohol, extraction with ether, and concentration, according to a modification of Zondek's method. Nine rhesus monkeys were treated-7 normal and 2 spayed during the course of injections. Grossly their gums assumed the appearance of \"pregnancy gingivitis.\"2 Microscopically the change was hyperplasia of the epithelium. The series of pregnant women also showed, microscopically, hyperplasia of the epithelium and, in addition, progressive loss of the keratin layer as pregnancy advanced from the fourth to the ninth month.

Effects of Subcutaneous Injections of Estro-Genic and Gonadotropic Hormones on Gums and Oral Mucous Membranes of Normal and Castrated Rhesus Monkeys

In two recent papers (1, 2), the writer and Blackberg reported observations on the gums of pregnant women and experiments with normal and castrated female rhesus monkeys. \"Pregnancy gingivitis\" (by us termed \"hormonal gingivitis\") was found in most of the pregnant women examined and the significant change in these gums was hyperplasia of the epithelium with progressive loss of the keratin layer as pregnancy advanced from the fourth to the ninth month. Similar pathosis was induced in the gums of normal rhesus monkeys injected with pregnancy urine extract. In the second study, with castrate monkeys, Folluetin injections resulted in a condition resembling Vincent's infection, whereas the gums of the estrogen-treated group became hard, pink, lost their pre-existing proneness to easy bleeding, and appeared better able to resist mouth infections. The present report concerns itself with six patients from Dr. Raphael Kurzrok's clinic for gynecological diseases, three of whom were being injected with estrogen (Progynon B-Schering Corporation) for amenorrhea and three with Folluetin (Squibb) for prolonged menstrual bleeding. Pre-treatment oral observations were not made, first examinations of gums being made two weeks to fifteen months after injections were begun. After gross observation of the gums, a

The Effect of Hormonal Treatment on the Gums and Oral Mucosa of Women (A) With the Use of Estrogen; (B) With the Use of the Gonadotropic Hormone of Pregnancy Urine

Daniel E. Ziskin

Papers

Glossodynia: A Study of Idiopathic Orolingual Pain

A comparison of oral and vaginal epithelial smears.

Pregnancy gingivitis: History, classification, etiology

Effects of Subcutaneous Injections of Estro-Genic and Gonadotropic Hormones on Gums and Oral Mucous Membranes of Normal and Castrated Rhesus Monkeys

The Effect of Hormonal Treatment on the Gums and Oral Mucosa of Women (A) With the Use of Estrogen; (B) With the Use of the Gonadotropic Hormone of Pregnancy Urine