D
Daniel Graf
Researcher at University of Alberta
Publications - Â 101
Citations - Â 6177
Daniel Graf is an academic researcher from University of Alberta. The author has contributed to research in topics: Bone morphogenetic protein & T cell. The author has an hindex of 34, co-authored 90 publications receiving 5795 citations. Previous affiliations of Daniel Graf include Hammersmith Hospital & Alexander Fleming Biomedical Sciences Research Center.
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Bone morphogenic protein signaling is a major determinant of dentate development
TL;DR: It is shown that bone morphogenic protein (Bmp) signaling is a critical regulator of embryonic dentate development, required for initiating neurogenesis in embryonic DG progenitors and required for the establishment of dentate neural stem cells postnatally.
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Immunological features of fibrodysplasia ossificans progressiva and the dysregulated BMP4 pathway
Frederick S. Kaplan,Eileen M. Shore,Rishi R. Gupta,Paul C. Billings,David L. Glaser,Robert J. Pignolo,Daniel Graf,Malek Kamoun +7 more
TL;DR: Features of the BMP4 signaling pathway that regulate the immune system are reviewed, and an integrated hypothesis for FOP is suggested that accounts for both BMP-related abnormalities and immunological features of the condition.
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Stem Cell Fate Determination during Development and Regeneration of Ectodermal Organs
TL;DR: Improving the current knowledge on the mechanisms involved in stem cell fate determination during organogenesis and homeostasis of ectodermal organs is crucial to develop effective stem cell-based therapies in order to regenerate or replace pathological and damaged tissues.
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Rational primer design greatly improves differential display-PCR (DD-PCR).
TL;DR: Modifying primer design shows that by modifying primer design, sampling of differentially expressed genes can be greatly enhanced and relevant genes can been isolated.
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The etiology of cleft palate formation in BMP7-deficient mice
Thaleia Kouskoura,Thaleia Kouskoura,Anastasiia Kozlova,Maria Alexiou,Susanne Blumer,Vasiliki Zouvelou,Christos Katsaros,Matthias Chiquet,Thimios A. Mitsiadis,Daniel Graf +9 more
TL;DR: F deformations in the oral cavity of Bmp7-deficient embryos such as the shorter and wider mandible were not solely responsible for cleft palate formation, which indicates a requirement for BMP7 for the coordination of both developmental and mechanistic aspects of palatogenesis.