Daniel J. Nevrivy

TL;DR: Two novel and related C2H2 zinc finger proteins that are highly expressed in the brain, CTIP1 and CTIP2 (COUPTF-interacting proteins1 and 2, respectively), were isolated and shown to interact with all members of the chicken ovalbumin upstream promoter transcription factor (Coup-TF) subfamily of orphan nuclear receptors.

TL;DR: The integrator protein, p300, was demonstrated to interact with mouse peroxisome proliferator-activated receptor α in a ligand-enhanced manner and can be considered a bona fide coactivator for this nuclear receptor.

TL;DR: Nuclear receptor corepressor appears to influence PPARα signaling pathways and, therefore, may modulate tissue responsiveness to peroxisome proliferators.

TL;DR: A novel, retinoic acid-induced gene, GRP1-associated scaffoldprotein (GRASP), was isolated from P19 embryonal carcinoma cells using a subtractive screening strategy and interacted strongly with the General Receptor for Phosphoinositides 1 (GRP1), a brefeldin A-insensitive guanine nucleotide exchange factor for the ADP-ribosylation factor family of proteins.

TL;DR: It is demonstrated that ARP1 and Ear2 form heterodimers in solution and on directly repeated response elements with high efficiency and a specificity differing from that of homodimeric complexes composed of either receptor.