D
Daniel M. D'Souza
Researcher at University of Edinburgh
Publications - 22
Citations - 2266
Daniel M. D'Souza is an academic researcher from University of Edinburgh. The author has contributed to research in topics: Rotaxane & Hydrogen bond. The author has an hindex of 14, co-authored 22 publications receiving 2063 citations. Previous affiliations of Daniel M. D'Souza include Heidelberg University & University of Düsseldorf.
Papers
More filters
Journal ArticleDOI
Multi-component syntheses of heterocycles by transition-metal catalysis
Daniel M. D'Souza,Thomas Müller +1 more
TL;DR: The underlying reaction based principles of transition-metal catalysis in multi-component syntheses of heterocycles, summarizes recent developments of palladium catalyzed MCR, and highlights the more recent contributions to MCR based heterocyclic synthesis by virtue of rhodium, ruthenium, and copper catalysis are outlined.
Journal ArticleDOI
Sequence-Specific Peptide Synthesis by an Artificial Small-Molecule Machine
Bartosz Lewandowski,Guillaume De Bo,John W. Ward,Marcus Papmeyer,Sonja Kuschel,María J. Aldegunde,Philipp M. E. Gramlich,Dominik Heckmann,Stephen M. Goldup,Daniel M. D'Souza,Antony E. Fernandes,David A. Leigh,David A. Leigh +12 more
TL;DR: The design, synthesis, and operation of an artificial small-molecule machine that travels along a molecular strand, picking up amino acids that block its path, to synthesize a peptide in a sequence-specific manner is reported on.
Journal ArticleDOI
A domino sequence consisting of insertion, coupling, isomerization, and Diels-Alder steps yields highly fluorescent spirocycles.
Journal ArticleDOI
Synthesis, structure and emission properties of spirocyclic benzofuranones and dihydroindolones: a domino insertion-coupling-isomerization- Diels-Alder approach to rigid fluorophores.
Daniel M. D'Souza,Daniel M. D'Souza,Alexander Kiel,Dirk-Peter Herten,Frank Rominger,Frank Rominger,Thomas Müller,Thomas Müller +7 more
TL;DR: DFT computations reveal that in the final pericyclic step the Diels-Alder termination is by far thermodynamically and kinetically favored over a possible Claisen rearrangement.
Journal ArticleDOI
Diversity-oriented syntheses of functional π-systems by multicomponent and domino reactions
Thomas Müller,Daniel M. D'Souza +1 more
TL;DR: In this article, a diversity-oriented π-electron system can be synthesized by applying multicomponent and domino reactions based upon alkyne activation by Sonogashira coupling, reactive triple or double bonds become the key functionality for se- quential and consecutive synthesis of heterocycles.