Daniel P. Brink

TL;DR: A brief summary of sources of lignin, methods of depolymerization, biological pathways for conversion of the lign in monomers and the analytical tools necessary for characterizing and evaluating key lignIn attributes are given.

TL;DR: The eLignin database is introduced, its dataset is used to map the reported ecological and biochemical diversity of the lignin microbial niches, and the findings are discussed.

TL;DR: The study was able to correlate the previously proposed beneficial effects of ira2∆, isu1 ∆ and hog1∆ on S. cerevisiae xylose uptake, with a change in the sugar signalome, suggesting that engineering of the signalome can improvexylose utilization.

TL;DR: The expansion of a panel of in vivo biosensor strains by adding a mutated galactose transporter with improved xylose affinity, and both the transporter and an oxidoreductasexylose pathway is expanded, suggesting that intracellular xyloses triggers a similar signal to carbon limitation in cells that are actively metabolizing xylOSE, in turn causing the low assimilation rates.

TL;DR: The identification of a vanillin reductase candidate gene whose deletion in a recombinant vanillin-accumulating P. putida strain almost completely alleviated the undesired vanillyl alcohol by-product yield represents an important step toward biotechnological production of vanillin from lignin using bacterial cell factories.