D
Daniel Wüstner
Researcher at University of Southern Denmark
Publications - 99
Citations - 3099
Daniel Wüstner is an academic researcher from University of Southern Denmark. The author has contributed to research in topics: Sterol & Sterol transport. The author has an hindex of 28, co-authored 88 publications receiving 2751 citations. Previous affiliations of Daniel Wüstner include Cornell University & Max Delbrück Center for Molecular Medicine.
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Spatiotemporal analysis of endocytosis and membrane distribution of fluorescent sterols in living cells
Daniel Wüstner,Nils J. Færgeman +1 more
TL;DR: These findings demonstrate that plasma membrane sterol is internalized by several endocytic pathways and does not require formation of microscopically resolvable sterol clusters or enrichment of sterol in surface caveolae.
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Two-photon time-lapse microscopy of BODIPY-cholesterol reveals anomalous sterol diffusion in chinese hamster ovary cells
TL;DR: An analytical model is presented that bridges the two regimes and fit this model to vesicle trajectories from control cells and cells with disrupted microtubule or actin filaments, which suggests the mobility of sterol-containing vesicles on the short time scale could reflect dynamic rearrangements of the cytoskeleton.
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Design of new fluorescent cholesterol and ergosterol analogs: Insights from theory.
Lina J. Nåbo,Nanna Holmgaard List,Sarah Witzke,Daniel Wüstner,Himanshu Khandelia,Jacob Kongsted +5 more
TL;DR: From the set of analogs explored, two probes are found to display favorable electronic transition properties as well as strong condensing abilities that can lead to the use of new efficient probes and aid in the understanding of the structural features of Chol and Erg that impart to them their unique effects on lipid membranes.
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Embedding beyond electrostatics—The role of wave function confinement
Lina J. Nåbo,Jógvan Magnus Haugaard Olsen,Nanna Holmgaard List,Lukasz M. Solanko,Daniel Wüstner,Jacob Kongsted +5 more
TL;DR: It is illustrated how the inclusion of non-electrostatic repulsion results in a successful identification of the intense π → π(∗) transition, which was not possible using an embedding method that only includes electrostatics.
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Imaging approaches for analysis of cholesterol distribution and dynamics in the plasma membrane.
TL;DR: Evidence from many experimental techniques converges towards a model of a homogeneous distribution of cholesterol with largely free and unhindered diffusion in both leaflets of the PM.