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Daniela C. Oniciu
Researcher at State Street Corporation
Publications - 9
Citations - 670
Daniela C. Oniciu is an academic researcher from State Street Corporation. The author has contributed to research in topics: In vivo & Chalcogen. The author has an hindex of 6, co-authored 9 publications receiving 590 citations. Previous affiliations of Daniela C. Oniciu include Texas A&M University & Pfizer.
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Journal ArticleDOI
Aromaticity as a cornerstone of heterocyclic chemistry.
Journal ArticleDOI
Long hydrocarbon chain ether diols and ether diacids that favorably alter lipid disorders in vivo.
Ralf Mueller,Jing Yang,Caiming Duan,Emil Pop,Lian Hao Zhang,Tian-Bao Huang,Anna Denisenko,Olga V Denisko,Daniela C. Oniciu,Charles L Bisgaier,Michael E Pape,Catherine Delaney Freiman,Brian Goetz,Clay T Cramer,Krista L Hopson,Jean-Louis H Dasseux +15 more
TL;DR: Long hydrocarbon chain ethers with bis-terminal hydroxyl or carboxyl groups have been synthesized and evaluated for their potential to favorably alter lipid disorders including metabolic syndrome and biological activity was found to be greatest for tetramethyl-substituted ether diols.
Journal ArticleDOI
Long Hydrocarbon Chain Keto Diols and Diacids that Favorably Alter Lipid Disorders in Vivo
Ralf Mueller,Jing Yang,Caiming Duan,Emil Pop,Otto J Geoffroy,Lian Hao Zhang,Tian-Bao Huang,Sergey Denisenko,Bruce H McCosar,Daniela C. Oniciu,Charles L Bisgaier,Michael E Pape,Catherine Delaney Freiman,Brian Goetz,Clay T Cramer,Krista L Hopson,Jean-Louis H Dasseux +16 more
TL;DR: Biological activity was found to be greatest in both in vivo and in vitro assays for the tetramethyl-substituted keto diacids and diols, and the least active compounds were shown to be the bis(arylmethyl) derivatives.
Journal ArticleDOI
Aromaticity as a Cornerstone of Heterocyclic Chemistry
Journal ArticleDOI
Influence of various central moieties on the hypolipidemic properties of long hydrocarbon chain diols and diacids.
Daniela C. Oniciu,Jean-Louis H Dasseux,Jing Yang,Ralf Mueller,Emil Pop,Anna Denysenko,Caiming Duan,Tian-Bao Huang,Lianhao Zhang,Brian R. Krause,Sandra L Drake,Narendra Lalwani,Clay T Cramer,Brian Goetz,Michael E Pape,Andrew McKee,Gregory J Fici,Janell M Lutostanski,Stephen C Brown,Charles L Bisgaier +19 more
TL;DR: Biological activity was enhanced by central substitution with O, C=O, S, S=O compared to the methylene analogues and was diminished for compounds with central functional groups such as carbamate, ester, urea, acetylmethylene, and hydroxymethylene.