抗原变异可使得多种致病微生物易于逃避宿主免疫应答。表达在感染红细胞表面的恶性疟原虫红细胞表面蛋白1（PfPMP1）与感染红细胞、内皮细胞、树突状细胞以及胎盘的单个或多个受体作用，在黏附及免疫逃避中起关键的作用。每个单倍体基因组var基因家族编码约60种成员，通过启动转录不同的var基因变异体为抗原变异提供了分子基础。

疟原虫var基因转换速率变化导致抗原变异[英]／Paul H, Robert P, Christodoulou Z, et al//Proc Natl Acad Sci U S A

I have developed "tennis elbow" from lugging this book around the past four weeks, but it is worth the pain, the effort, and the aspirin. It is also worth the (relatively speaking) bargain price. Including appendixes, this book contains 894 pages of text. The entire panorama of the neural sciences is surveyed and examined, and it is comprehensive in its scope, from genomes to social behaviors. The editors explicitly state that the book is designed as "an introductory text for students of biology, behavior, and medicine," but it is hard to imagine any audience, interested in any fragment of neuroscience at any level of sophistication, that would not enjoy this book. The editors have done a masterful job of weaving together the biologic, the behavioral, and the clinical sciences into a single tapestry in which everyone from the molecular biologist to the practicing psychiatrist can find and appreciate his or

Principles of Neural Science

Introduction 1. Woman's Place in Man's Life Cycle 2. Images of Relationship 3. Concepts of Self and Morality 4. Crisis and Transition 5. Women's Rights and Women's Judgment 6. Visions of Maturity References Index of Study Participants General Index

In a Different Voice. Psychological Theory and Women’s Development. Cambridge, MA (Harvard University Press) 1982.

Research on moral judgment has been dominated by rationalist models, in which moral judgment is thought to be caused by moral reasoning. The author gives 4 reasons for considering the hypothesis that moral reasoning does not cause moral judgment; rather, moral reasoning is usually a post hoc construction, generated after a judgment has been reached. The social intuitionist model is presented as an alternative to rationalist models. The model is a social model in that it deemphasizes the private reasoning done by individuals and emphasizes instead the importance of social and cultural influences. The model is an intuitionist model in that it states that moral judgment is generally the result of quick, automatic evaluations (intuitions). The model is more consistent than rationalist models with recent findings in social, cultural, evolutionary, and biological psychology, as well as in anthropology and primatology.

https://www.motherjones.com/files/emotional_dog_and_rational_tail.pdf

The emotional dog and its rational tail: a social intuitionist approach to moral judgment.

Part I. Experimental Studies: 2. Experiment in psychology 3. Experiments on perceiving III Experiments on imaging 4-8. Experiments on remembering: (a) The method of description (b) The method of repeated reproduction (c) The method of picture writing (d) The method of serial reproduction (e) The method of serial reproduction picture material 9. Perceiving, recognizing, remembering 10. A theory of remembering 11. Images and their functions 12. Meaning Part II. Remembering as a Study in Social Psychology: 13. Social psychology 14. Social psychology and the matter of recall 15. Social psychology and the manner of recall 16. Conventionalism 17. The notion of a collective unconscious 18. The basis of social recall 19. A summary and some conclusions.

Remembering. A Study in Experimental and Social Psychology, Cambridge (University Press) 1964.

Contents: Preface. J.R. Rest, Background: Theory and Research. S.P. McNeel, College Teaching and Student Moral Development. L.J. Duckett, M.B. Ryden, Education for Ethical Nursing Practice. F-Y. Chang, School Teachers' Moral Reasoning. N.A. Sprinthall, Counseling and Social Role Taking: Promoting Moral and Ego Development. L.A. Ponemon, D.R.L. Gabhart, Ethical Reasoning Research in the Accounting and Auditing Professions. M.J. Bebeau, Influencing the Moral Dimensions of Dental Practice. D.J. Self, D.C. Baldwin, Jr., Moral Reasoning in Medicine. D.J. Self, M. Olivarez, D.C. Baldwin, Jr., Moral Reasoning in Veterinary Medicine. B.J.L. Bredemeier, D.L.L. Shields, Applied Ethics and Moral Reasoning in Sport. T. Westbrook, Tracking the Moral Development of Journalists: A Look at Them and Their Work. S. Thoma, Moral Judgments and Moral Action. J.R. Rest, D. Narvaez, Summary: What's Possible?

Moral Development in the Professions : Psychology and Applied Ethics

The Denning Issues Test, Version 2 (DIT2), updates dilemmas and items, shortens the original Defining Issues Test (DIT1) of moral judgment, and purges fewer participants for doubtful response reliability DIT1 has been used for over 25 years DIT2 makes 3 changes: in dilemmas and items, in the algorithm of indexing, and in the method of detecting unreliable participants With all 3 changes, DIT2 is an improvement over DIT1 The validity criteria for DIT2 are (a) significant age and educational differences among 9th graders, high school graduates, college seniors, and students in graduate and professional schools; (b) prediction of views on public policy issues (eg, abortion, religion in schools, rights of homosexuals, women's roles); (c) internal reliability; and (d) correlation with DIT1 However, the increased power of DIT2 over DIT1 is primarily due to the new methods of analysis (a new index called N2, new checks) rather than to changes in dilemmas, items, or instructions Although DIT2 presents updated dilemmas and smoother wording in a shorter test (practical improvements), the improvements in analyses account for the validity improvements

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DIT2: Devising and testing a revised instrument of moral judgment.

/pdf/handbook-of-moral-and-character-education-3vqrj1xo43.pdf

Handbook of Moral and Character Education

Kohlberg's work in moral judgement has been criticised by many philosophers and psychologists. Building on Kohlberg's core assumptions, we propose a model of moral judgement (hereafter the neo-Kohlbergian approach) that addresses these concerns. Using 25 years of data gathered with the Defining Issues Test (DIT), we present an overview of Minnesota's neo-Kohlbergian approach, using Kohlberg's basic starting points, ideas from Cognitive Science (especially schema theory), and developments in moral philosophy.

/pdf/a-neo-kohlbergian-approach-to-morality-research-3ke2ofbb6z.pdf

A Neo-Kohlbergian Approach to Morality Research

“Macromorality” concerns the formal structure of society, as defined by institutions, rules, and roles “Micromorality” concerns the particular face-to-face relations that people have in everyday life Kohlbergian theories are most useful for issues of macromorality The Defining Issues Test (DIT) derives from Kohlberg's approach but makes several departures, including defining cognitive structures in terms of schemas instead of stages, reformulating the definition of postconventional moral thinking, and using different research strategies The validity of the DIT is based on seven criteria (briefly discussed), and hundreds of studies have produced significant trends Recent research derived from schema theory produces novel phenomena that link our theory of moral schemas more closely with information processing and decision making

/pdf/a-neo-kohlbergian-approach-the-dit-and-schema-theory-13393lb1zo.pdf

Darcia Narvaez

Papers

Moral Development in the Professions : Psychology and Applied Ethics

DIT2: Devising and testing a revised instrument of moral judgment.

Handbook of Moral and Character Education

A Neo-Kohlbergian Approach to Morality Research

A Neo-Kohlbergian Approach: The DIT and Schema Theory