D
Dario Ponce de Leon
Researcher at Pfizer
Publications - 15
Citations - 429
Dario Ponce de Leon is an academic researcher from Pfizer. The author has contributed to research in topics: Tofacitinib & Janus kinase inhibitor. The author has an hindex of 6, co-authored 15 publications receiving 123 citations.
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Journal ArticleDOI
Tofacitinib in Patients Hospitalized with Covid-19 Pneumonia.
Patrícia O. Guimarães,Daniel Quirk,Remo H. Furtado,Lilia N. Maia,José F. Saraiva,Murillo Oliveira Antunes,Roberto Kalil Filho,Vagner Madrini Junior,Alexandre de Matos Soeiro,Alexandre P. Tognon,Viviane C Veiga,Priscilla de Aquino Martins,Diogo D.F. Moia,Bruna S. Sampaio,Silvia R.L. Assis,Ronaldo V P Soares,Luciana P.A. Piano,Kleber Castilho,Roberta G.R.A.P. Momesso,Frederico Monfardini,Hélio Penna Guimarães,Dario Ponce de Leon,Majori Dulcine,Marcia Pinheiro,Levent M. Gunay,J. Jasper Deuring,Luiz Vicente Rizzo,Tamas Koncz,Otavio Berwanger +28 more
TL;DR: Among patients hospitalized with Covid-19 pneumonia, tofacitinib led to a lower risk of death or respiratory failure through day 28 than placebo, and the proportional odds of having a worse score on the eight-level ordinal scale with tofacinib, as compared with placebo.
Journal ArticleDOI
Comparison of patient and physician perspectives in the management of rheumatoid arthritis: results from global physician- and patient-based surveys
Allan Gibofsky,Allan Gibofsky,James Galloway,Joern Kekow,Cristiano A. F. Zerbini,Maria de la Vega,Gavin Lee,Eun Young Lee,Catalin Codreanu,Cheryl L. Koehn,Kathy Steinberg,Eustratios Bananis,Dario Ponce de Leon,A. Maniccia,Ara Dikranian +14 more
TL;DR: The results of these surveys highlight the impact of RA on patients, and a discrepancy between patient and physician views on communication, and further research is needed on improving patient–physician dialogue, shared goal-setting, and treatment planning.
Journal ArticleDOI
Review of the epidemiology and burden of ulcerative colitis in Latin America.
Paulo Gustavo Kotze,Flavio Steinwurz,Carlos Francisconi,Cyrla Zaltman,Marcia Pinheiro,Leonardo Salese,Dario Ponce de Leon +6 more
TL;DR: Data from published studies reporting demographics and clinical aspects of UC in Latin America are reviewed to further understand epidemiology and disease burden and to influence therapeutic approaches and the development of strategies to improve healthcare access and patient outcomes.
Journal ArticleDOI
Incidence Rates of Interstitial Lung Disease Events in Tofacitinib-Treated Rheumatoid Arthritis Patients: Post Hoc Analysis From 21 Clinical Trials.
Gustavo Citera,Eduardo Mysler,Hugo Madariaga,Mario H. Cardiel,Oswaldo Castañeda,Aryeh Fischer,Pascal Richette,Sandra Chartrand,Jin Kyun Park,Sander Strengholt,Jose Luis Rivas,Amit V. Thorat,Tanya Girard,Kenneth Kwok,Lisy Wang,Dario Ponce de Leon +15 more
TL;DR: Across P1/2/3/4/long-term extension studies, incidence rates for ILD events were 0.18 following tofacitinib treatment, and ILD Events were associated with known risk factors for I LD in RA.
Journal ArticleDOI
Treatment Mode Preferences in Rheumatoid Arthritis: Moving Toward Shared Decision-Making.
Peter C. Taylor,Neil Betteridge,T. Michelle Brown,John Woolcott,Alan J Kivitz,Cristiano A. F. Zerbini,Diane Whalley,Oyebimpe Olayinka-Amao,Connie Chen,P. Dahl,Dario Ponce de Leon,David Gruben,Lara Fallon +12 more
TL;DR: Patients with rheumatoid arthritis may benefit from discussions with their healthcare professionals and/or patient support groups, regarding RA treatment modes, to facilitate shared decision-making.