D
David A. Cotter
Researcher at University of Windsor
Publications - 58
Citations - 894
David A. Cotter is an academic researcher from University of Windsor. The author has contributed to research in topics: Dictyostelium discoideum & Spore germination. The author has an hindex of 17, co-authored 58 publications receiving 886 citations.
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Journal ArticleDOI
Adenylyl Cyclase G, an Osmosensor Controlling Germination of Dictyostelium Spores
Saskia van Es,Kiran J. Virdy,Geoffrey S. Pitt,Marcel Meima,Todd W. Sands,Peter N. Devreotes,David A. Cotter,Pauline Schaap +7 more
TL;DR: Data indicate that ACG is an osmosensor controlling spore germination through activation of protein kinase A, which is a fairly universal constraint for spore and seed germination.
Journal ArticleDOI
Patterning of development in Dictyostelium discoideum: factors regulating growth, differentiation, spore dormancy, and germination.
TL;DR: A source and sink model is presented in which the assimilation of ammonia plays a major role in determining cell fate and pattern formation in Dictyostelium discoideum.
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Acid-activatable Cysteine Proteinases in the Cellular Slime Mold Dictyostelium discoideum
TL;DR: A developmental model is presented which suggests that the crypticity of the cysteine proteinases in dormant spores may be governed by proton pumps and endogenous lysosomotropic agents.
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High cAMP in spores of Dictyostelium discoideum: association with spore dormancy and inhibition of germination.
Kiran J. Virdy,Todd W. Sands,Susan H. Kopko,Saskia van Es,Marcel Meima,Pauline Schaap,David A. Cotter +6 more
TL;DR: Evidence is provided for continued cAMP signalling in spores up to 18 d after sporulation and for linkages between elevated cAMP, spore deactivation and inhibition of spontaneous germination, supporting the hypothesis that exogenously activated and autoactivated spores germinate by different mechanisms.
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Ammonium phosphate in sori of Dictyostelium discoideum promotes spore dormancy through stimulation of the osmosensor ACG
TL;DR: It was concluded that the transcription and translation of GS is not environmentally regulated but is an integral part of the germination process, preparing nascent amoebae for vegetative growth.